product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human FGFR3 Antibody
catalog :
MAB7661-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
136318
reactivity :
human
application :
western blot, neutralization, immunohistochemistry - frozen section
more info or order :
citations: 3
Reference
Iram T, Kern F, Kaur A, Myneni S, Morningstar A, Shin H, et al. Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17. Nature. 2022;605:509-515 pubmed publisher
Di Maggio N, Mehrkens A, Papadimitropoulos A, Schaeren S, Heberer M, Banfi A, et al. Fibroblast growth factor-2 maintains a niche-dependent population of self-renewing highly potent non-adherent mesenchymal progenitors through FGFR2c. Stem Cells. 2012;30:1455-64 pubmed publisher
Shin J, Min M, Larrieu Lahargue F, Canron X, Kunstfeld R, Nguyen L, et al. Prox1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: a role for FGF signaling in lymphangiogenesis. Mol Biol Cell. 2006;17:576-84 pubmed
product information
master code :
MAB7661
SKU :
MAB7661-100
product name :
Human FGFR3 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Human FGFR3 Antibody from R&D Systems is a mouse monoclonal antibody to FGFR3. This antibody reacts with human. The Human FGFR3 Antibody has been validated for the following applications: Neutralization,Immunohistochemistry-Frozen,Western Blot.
target :
FGFR3
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
136318
conjugate :
Unconjugated
host :
Mouse
immunogen :
Pool of NS0-derived recombinant human FGFáR3 alpha (IIIb) and Sf21-derived FGF R3 alphaá(IIIc)
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects the IIIb and IIIc isoforms of human FGF R3. It does not cross-react with mouse FGF R3 or with any isoforms of recombinant human (rh) FGFáR1 or rhFGFáR2.
gene symbol :
FGFR3
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
FGF R3 Inhibition of FGF acidic-dependent Cell Proliferation and Neutralization by Human FGF R3 Antibody.
applications :
Neutralization,Immunohistochemistry-Frozen,Western Blot
USD :
469 USD
alt names :
CD333, CEK, EC 2.7.10, FGF R3, fibroblast growth factor receptor 3, HSFGFR3EX, JTK4, JTK4thanatophoric dwarfism
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.