Mouse Tyro3/Dtk Antibody | R&D Systems MAB759 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Tyro3/Dtk Antibody

catalog :

MAB759

quantity :

500 ug (also 25 ug)

price :

559 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

109646

reactivity :

mouse, rat

application :

western blot, ELISA, immunocytochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot; mouse	Deng T, Zhang Y, Chen Q, Yan K, Han D. Toll-like receptor-mediated inhibition of Gas6 and ProS expression facilitates inflammatory cytokine production in mouse macrophages. Immunology. 2012;135:40-50 pubmed publisher
western blot; mouse	Shang T, Zhang X, Wang T, Sun B, Deng T, Han D. Toll-like receptor-initiated testicular innate immune responses in mouse Leydig cells. Endocrinology. 2011;152:2827-36 pubmed publisher
	Zewdie E, Edwards G, Hunter D, EARP H, Holtzhausen A. MerTK Induces Dysfunctional Dendritic Cells by Metabolic Reprogramming. Cancer Immunol Res. 2024;12:1268-1285 pubmed publisher
	Ni J, Lin M, Jin Y, Li J, Guo Y, Zhou J, et al. Gas6 Attenuates Sepsis-Induced Tight Junction Injury and Vascular Endothelial Hyperpermeability via the Axl/NF-κB Signaling Pathway. Front Pharmacol. 2019;10:662 pubmed publisher
	Kasikara C, Davra V, Calianese D, Geng K, Spires T, Quigley M, et al. Pan-TAM Tyrosine Kinase Inhibitor BMS-777607 Enhances Anti-PD-1 mAb Efficacy in a Murine Model of Triple-Negative Breast Cancer. Cancer Res. 2019;79:2669-2683 pubmed publisher
	Fujimori T, Grabiec A, Kaur M, Bell T, Fujino N, Cook P, et al. The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung. Mucosal Immunol. 2015;8:1021-1030 pubmed publisher
	Qi N, Liu P, Zhang Y, Wu H, Chen Y, Han D. Development of a spontaneous liver disease resembling autoimmune hepatitis in mice lacking tyro3, axl and mer receptor tyrosine kinases. PLoS ONE. 2013;8:e66604 pubmed publisher
	Taichman R, Patel L, Bedenis R, Wang J, Weidner S, Schumann T, et al. GAS6 receptor status is associated with dormancy and bone metastatic tumor formation. PLoS ONE. 2013;8:e61873 pubmed publisher
	Jung Y, Shiozawa Y, Wang J, McGregor N, Dai J, Park S, et al. Prevalence of prostate cancer metastases after intravenous inoculation provides clues into the molecular basis of dormancy in the bone marrow microenvironment. Neoplasia. 2012;14:429-39 pubmed

product information

master code :

MAB759

SKU :

MAB759

product name :

Mouse Tyro3/Dtk Antibody

unit size :

500 ug (also 25 ug)

description :

The Mouse Tyro3/Dtk Antibody from R&D Systems is a rat monoclonal antibody to Dtk/TYRO3. This antibody reacts with mouse,rat. The Mouse Tyro3/Dtk Antibody has been validated for the following applications: Mass Spectrometry,Flow Cytometry,Western Blot,ELISA Capture (Matched Antibody Pair),Immunocytochemistry.

target :

Tyro3/Dtk

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

109646

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse Tyro3/Dtk, Ala31-Ser418, Accession # P55144

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse,Rat

specificity :

Detects mouse Tyro3/Dtk extracellular domain in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human Tyro3/Dtk, recombinant mouse (rm) Mer, or rmAxl is observed.

gene symbol :

Tyro3

accessionNumbers :

P55144

applications :

Mass Spectrometry,Flow Cytometry,Western Blot,ELISA Capture (Matched Antibody Pair),Immunocytochemistry

USD :

559 USD

alt names :

Brt, BYK, Dtk, EC 2.7.10, EC 2.7.10.1, FLJ16467, RSE, Sky, Tif, TYRO3 protein tyrosine kinase, Tyrosine-protein kinase byk, Tyrosine-protein kinase DTK, tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase RSE, Tyrosine-protein kinase SKY

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage