Human BMP-4 Antibody | R&D Systems MAB757 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human BMP-4 Antibody

catalog :

MAB757

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

66119

reactivity :

human, mouse

application :

western blot, neutralization

citations: 12

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:500; fig 3q	Dupays L, Towers N, Wood S, David A, Stuckey D, Mohun T. Furin, a transcriptional target of NKX2-5, has an essential role in heart development and function. PLoS ONE. 2019;14:e0212992 pubmed publisher
	Patel A, Vipparthi K, Thatikonda V, Arun I, Bhattacharjee S, Sharan R, et al. A subtype of cancer-associated fibroblasts with lower expression of alpha-smooth muscle actin suppresses stemness through BMP4 in oral carcinoma. Oncogenesis. 2018;7:78 pubmed publisher
	Blanchette Farra N, Kita D, Konstorum A, Tesfay L, Lemler D, Hegde P, et al. Contribution of three-dimensional architecture and tumor-associated fibroblasts to hepcidin regulation in breast cancer. Oncogene. 2018;37:4013-4032 pubmed publisher
	Sallon C, Callebaut I, Boulay I, Fontaine J, Logeart Avramoglou D, Henriquet C, et al. Thrombospondin-1 (TSP-1), a new bone morphogenetic protein-2 and -4 (BMP-2/4) antagonist identified in pituitary cells. J Biol Chem. 2017;292:15352-15368 pubmed publisher
	Herrera B, Inman G. A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins. Identification and quantification of BMP4, BMP6 and BMP9 in bovine and human serum. BMC Cell Biol. 2009;10:20 pubmed publisher
	Jeanpierre S, Nicolini F, Kaniewski B, Dumontet C, Rimokh R, Puisieux A, et al. BMP4 regulation of human megakaryocytic differentiation is involved in thrombopoietin signaling. Blood. 2008;112:3154-63 pubmed publisher
	Kane R, Godson C, O Brien C. Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis. Mol Vis. 2008;14:1138-48 pubmed
	Zode G, Clark A, Wordinger R. Activation of the BMP canonical signaling pathway in human optic nerve head tissue and isolated optic nerve head astrocytes and lamina cribrosa cells. Invest Ophthalmol Vis Sci. 2007;48:5058-67 pubmed
	Fuller M, DeChant A, Rothstein B, Caprariello A, Wang R, Hall A, et al. Bone morphogenetic proteins promote gliosis in demyelinating spinal cord lesions. Ann Neurol. 2007;62:288-300 pubmed
	Bleuming S, Kodach L, Garcia Leon M, Richel D, Peppelenbosch M, Reitsma P, et al. Altered bone morphogenetic protein signalling in the Helicobacter pylori-infected stomach. J Pathol. 2006;209:190-7 pubmed
	Moser M, Binder O, Wu Y, Aitsebaomo J, Ren R, Bode C, et al. BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation. Mol Cell Biol. 2003;23:5664-79 pubmed
	van den Brink G, Hardwick J, Tytgat G, Brink M, ten Kate F, van Deventer S, et al. Sonic hedgehog regulates gastric gland morphogenesis in man and mouse. Gastroenterology. 2001;121:317-28 pubmed

product information

brand :

R&D Systems

master code :

MAB757

SKU :

MAB757-100

product name :

Human BMP-4 Antibody

description :

The Human BMP-4 Antibody from R&D Systems is a mouse monoclonal antibody to BMP-4. This antibody reacts with human. The Human BMP-4 Antibody has been validated for the following applications: Western Blot, Neutralization.

target :

BMP-4

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

66119

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human BMP-4, Ser293-Arg408, Accession # P12644

isotype :

IgG2b

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human BMP-4 in direct ELISAs and Western blots. This antibody shows approximately 5% cross-reactivity with recombinant human BMP-2.

gene symbol :

BMP4

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB757

accessionNumbers :

P12644

applications :

Western Blot, Neutralization

2020 USD :

339

2021 USD :

359 USD

alt names :

BMP2B, BMP-2B, BMP2B1, BMP2BMCOPS6, BMP4, BMP-4, Bone morphogenetic protein 2B, bone morphogenetic protein 4, DVR4, MCOPS6, OFC11, ZYME

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.