product summary
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company name :
R&D Systems
product type :
antibody
product name :
BMP-4 Antibody
catalog :
MAB757-100
quantity :
100 ug (also 500 ug, 25 ug)
price :
442 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
66119
reactivity :
human
application :
western blot, neutralization
more info or order :
citations: 13
Reference |
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Kane R, Godson C, O Brien C. Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis. Mol Vis. 2008;14:1138-48 pubmed
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Zode G, Clark A, Wordinger R. Activation of the BMP canonical signaling pathway in human optic nerve head tissue and isolated optic nerve head astrocytes and lamina cribrosa cells. Invest Ophthalmol Vis Sci. 2007;48:5058-67 pubmed
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Fuller M, DeChant A, Rothstein B, Caprariello A, Wang R, Hall A, et al. Bone morphogenetic proteins promote gliosis in demyelinating spinal cord lesions. Ann Neurol. 2007;62:288-300 pubmed
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Bleuming S, Kodach L, Garcia Leon M, Richel D, Peppelenbosch M, Reitsma P, et al. Altered bone morphogenetic protein signalling in the Helicobacter pylori-infected stomach. J Pathol. 2006;209:190-7 pubmed
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Moser M, Binder O, Wu Y, Aitsebaomo J, Ren R, Bode C, et al. BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation. Mol Cell Biol. 2003;23:5664-79 pubmed
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van den Brink G, Hardwick J, Tytgat G, Brink M, ten Kate F, van Deventer S, et al. Sonic hedgehog regulates gastric gland morphogenesis in man and mouse. Gastroenterology. 2001;121:317-28 pubmed
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image
image 1 :

Alkaline Phosphatase Production Induced by BMP-4 and Neutralization by Human BMP-4 Antibody.
product information
brand :
R&D Systems
master code :
MAB757
SKU :
MAB757-100
product name :
BMP-4 Antibody
description :
The Human BMP-4 MAb (Clone 66119) from R&D Systems is a mouse monoclonal antibody to BMP-4. This antibody reacts with human. The Human BMP-4 MAb (Clone 66119) has been validated for the following applications: Western Blot, Neutralization.
target :
BMP-4
category :
Primary Antibodies
sizes available :
100 ug (also 500 ug, 25 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
66119
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human BMP-4, Ser293-Arg408, Accession # P12644
isotype :
IgG2b
purity :
Protein A or G purified from ascites
species :
Human
specificity :
Detects human BMP-4 in direct ELISAs and Western blots
gene symbol :
BMP4
endotoxin note :
<0.10 EU per 1 µg of the antibody by the LAL method.
accessionNumbers :
P12644
applications :
Western Blot, Neutralization
USD :
442 USD
alt names :
BMP2B, BMP-2B, BMP2B1, BMP2BMCOPS6, BMP4, BMP-4, Bone morphogenetic protein 2B, bone morphogenetic protein 4, DVR4, MCOPS6, OFC11, ZYME
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information

R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
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