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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse Tyrosine Hydroxylase Antibody
catalog :
MAB7566
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
779427
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry
more info or order :
citations: 17
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 0.5 ug/ml
Abu El Asrar A, Siddiquei M, Nawaz M, Geboes K, Mohammad G. The proinflammatory cytokine high-mobility group box-1 mediates retinal neuropathy induced by diabetes. Mediators Inflamm. 2014;2014:746415 pubmed publisher
He S, Liu J, Xue Y, Fu T, Li Z. Sympathetic Nerves Coordinate Corneal Epithelial Wound Healing by Controlling the Mobilization of Ly6Chi Monocytes From the Spleen to the Injured Cornea. Invest Ophthalmol Vis Sci. 2023;64:13 pubmed publisher
Dai W, Yang M, Xia P, Xiao C, Huang S, Zhang Z, et al. A functional role of meningeal lymphatics in sex difference of stress susceptibility in mice. Nat Commun. 2022;13:4825 pubmed publisher
Panicker N, Kam T, Wang H, Neifert S, Chou S, Kumar M, et al. Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson's disease. Neuron. 2022;: pubmed publisher
Apostol C, Bernard K, Tanguturi P, Molnar G, Bartlett M, Szab xf2 L, et al. Design and Synthesis of Brain Penetrant Glycopeptide Analogues of PACAP With Neuroprotective Potential for Traumatic Brain Injury and Parkinsonism. Front Drug Discov (Lausanne). 2022;1: pubmed publisher
Fernandez Parrilla M, Reyes Corona D, Flores Martinez Y, Nadella R, Bannon M, Escobedo L, et al. Cerebral dopamine neurotrophic factor transfection in dopamine neurons using neurotensin-polyplex nanoparticles reverses 6-hydroxydopamine-induced nigrostriatal neurodegeneration. Neural Regen Res. 2022;17:854-866 pubmed publisher
Jasso K, Kamba T, Zimmerman A, Bansal R, Engle S, Everett T, et al. An N-terminal fusion allele to study melanin concentrating hormone receptor 1. Genesis. 2021;59:e23438 pubmed publisher
Huang S, Kuri P, Aubert Y, Brewster M, Li N, Farrelly O, et al. Lgr6 marks epidermal stem cells with a nerve-dependent role in wound re-epithelialization. Cell Stem Cell. 2021;28:1582-1596.e6 pubmed publisher
Chen S, Han Y, Yang L, Kim T, Nair M, Harschnitz O, et al. SARS-CoV-2 Infection Causes Dopaminergic Neuron Senescence. Res Sq. 2021;: pubmed publisher
Liu D, Li J, Wu J, Dai J, Chen X, Huang Y, et al. Monochromatic Blue Light Activates Suprachiasmatic Nucleus Neuronal Activity and Promotes Arousal in Mice Under Sevoflurane Anesthesia. Front Neural Circuits. 2020;14:55 pubmed publisher
Fan Y, Zeng F, Brown R, Price J, Jones T, Zhu M. Transcription Factors Phox2a/2b Upregulate Expression of Noradrenergic and Dopaminergic Phenotypes in Aged Rat Brains. Neurotox Res. 2020;38:793-807 pubmed publisher
Lin M, Lin C, Chen Y, Yang H, Hung S. Celastrol Inhibits Dopaminergic Neuronal Death of Parkinson's Disease through Activating Mitophagy. Antioxidants (Basel). 2019;9: pubmed publisher
Kim B, Choi S, Shin J, Kim J, Kang I, Lee B, et al. Single-Factor SOX2 Mediates Direct Neural Reprogramming of Human Mesenchymal Stem Cells via Transfection of In Vitro Transcribed mRNA. Cell Transplant. 2018;:963689718771885 pubmed publisher
LITTLE D, Luft C, Mosaku O, Lorvellec M, Yao Z, Paillusson S, et al. A single cell high content assay detects mitochondrial dysfunction in iPSC-derived neurons with mutations in SNCA. Sci Rep. 2018;8:9033 pubmed publisher
Leem E, Kim H, Choi M, Kim S, Oh Y, Lee K, et al. Upregulation of neuronal astrocyte elevated gene-1 protects nigral dopaminergic neurons in vivo. Cell Death Dis. 2018;9:449 pubmed publisher
Schommer J, Marwarha G, Schommer T, Flick T, Lund J, Ghribi O. 27-Hydroxycholesterol increases α-synuclein protein levels through proteasomal inhibition in human dopaminergic neurons. BMC Neurosci. 2018;19:17 pubmed publisher
Lin J, Chen C, Yang H, Chen Y, Hung S. Electroacupuncture Promotes Recovery of Motor Function and Reduces Dopaminergic Neuron Degeneration in Rodent Models of Parkinson's Disease. Int J Mol Sci. 2017;18: pubmed publisher
product information
master code :
MAB7566
SKU :
MAB7566
product name :
Human/Mouse Tyrosine Hydroxylase Antibody
unit size :
100 ug (also 25 ug)
description :
The Human/Mouse Tyrosine Hydroxylase Antibody from R&D Systems is a mouse monoclonal antibody to Tyrosine Hydroxylase. This antibody reacts with human,mouse,rat. The Human/Mouse Tyrosine Hydroxylase Antibody has been validated for the following applications: Immunohistochemistry,Flow Cytometry,Western Blot,Immunofluorescence,Immunocytochemistry,Simple Western.
target :
Tyrosine Hydroxylase
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
779427
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human Tyrosine Hydroxylase, Ala278-Tyr401, Accession # P07101
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Rat
specificity :
Detects human Tyrosine Hydroxylase in direct ELISAs and human, mouse and rat Tyrosine Hydroxylase in Western blots. In direct ELISAs, no cross-reactivity with recombinant human Tryptophan Hydroxylase-1 is observed.
gene symbol :
TH
top caption :
Detection of Human, Mouse, and Rat Tyrosine Hydroxylase antibody by Western Blot.
accessionNumbers :
P07101
applications :
Immunohistochemistry,Flow Cytometry,Western Blot,Immunofluorescence,Immunocytochemistry,Simple Western
USD :
499 USD
alt names :
DYT14, DYT5b, EC 1.14.16, EC 1.14.16.2, TH, TYH, TYH dystonia 14, Tyrosine 3-hydroxylase, tyrosine 3-monooxygenase, tyrosine hydroxylase
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.