product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human CCL28 Antibody
catalog :
MAB717
quantity :
500 ug (also 25 ug)
price :
569 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
62705
reactivity :
human, mouse
application :
western blot, neutralization, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 6
Reference
Nayrac M, Requena M, Loiseau C, Cazabat M, Suc B, Carrere N, et al. Th22 cells are efficiently recruited in the gut by CCL28 as an alternative to CCL20 but do not compensate for the loss of Th17 cells in treated HIV-1-infected individuals. Mucosal Immunol. 2021;14:219-228 pubmed publisher
Esposito E, Ahn B, Shi J, Nakamura Y, Park J, Mandeville E, et al. Brain-to-cervical lymph node signaling after stroke. Nat Commun. 2019;10:5306 pubmed publisher
Zsiros E, Duttagupta P, Dangaj D, Li H, Frank R, Garrabrant T, et al. The Ovarian Cancer Chemokine Landscape Is Conducive to Homing of Vaccine-Primed and CD3/CD28-Costimulated T Cells Prepared for Adoptive Therapy. Clin Cancer Res. 2015;21:2840-50 pubmed publisher
Facciabene A, Peng X, Hagemann I, Balint K, Barchetti A, Wang L, et al. Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells. Nature. 2011;475:226-30 pubmed publisher
Eksteen B, Miles A, Curbishley S, Tselepis C, Grant A, Walker L, et al. Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10. J Immunol. 2006;177:593-603 pubmed
Hieshima K, Ohtani H, Shibano M, Izawa D, Nakayama T, Kawasaki Y, et al. CCL28 has dual roles in mucosal immunity as a chemokine with broad-spectrum antimicrobial activity. J Immunol. 2003;170:1452-61 pubmed
product information
master code :
MAB717
SKU :
MAB717
product name :
Human CCL28 Antibody
unit size :
500 ug (also 25 ug)
description :
The Human CCL28 Antibody from R&D Systems is a mouse monoclonal antibody to CCL28. This antibody reacts with human,mouse. The Human CCL28 Antibody has been validated for the following applications: ELISA Development,Western Blot,Neutralization,Functional Assay,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen.
target :
CCL28
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
62705
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human CCL28, Ile23-Tyr127, Accession # Q9NRJ3
isotype :
IgG1
purity :
Protein A or G purified from ascites
species :
Human,Mouse
specificity :
Detects human CCL28 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human CCL1, 2, 3, 4, 5, 7, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, recombinant mouse CCL1, 2, 3, 4, 5, 6, 7, 9, 11, 19, 21, 22, 25, or recombinant rat CCL20 is observed.
gene symbol :
CCL28
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Chemotaxis Induced by CCL28 and Neutralization by Human CCL28 Antibody.
accessionNumbers :
Q9NRJ3
applications :
ELISA Development,Western Blot,Neutralization,Functional Assay,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen
USD :
569 USD
alt names :
CCL28, chemokine (C-C motif) ligand 28, MEC, member 28, MGC71902, Protein CCK1, VIC
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.