Mouse FGFR2 (IIIc) Antibody | R&D Systems MAB716-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse FGFR2 (IIIc) Antibody

catalog :

MAB716-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

459 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

133706

reactivity :

human, mouse, bovine

application :

western blot, immunohistochemistry, neutralization, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 5

Reference
Devi H, Kumar S, Konyak Y, Bharati J, Bhimte A, Pandey Y, et al. Expression and functional role of fibroblast growth factors (FGF) in placenta during different stages of pregnancy in water buffalo (Bubalus bubalis). Theriogenology. 2020;143:98-112 pubmed publisher
Coutu D, Kokkaliaris K, Kunz L, Schroeder T. Multicolor quantitative confocal imaging cytometry. Nat Methods. 2018;15:39-46 pubmed publisher
Nonogaki K, Kaji T, Yamazaki T, Murakami M. Treatment with FGFR2-IIIc monoclonal antibody suppresses weight gain and adiposity in KKAy mice. Nutr Diabetes. 2016;6:e233 pubmed publisher
Shalhoub V, Ward S, Sun B, Stevens J, Renshaw L, Hawkins N, et al. Fibroblast growth factor 23 (FGF23) and alpha-klotho stimulate osteoblastic MC3T3.E1 cell proliferation and inhibit mineralization. Calcif Tissue Int. 2011;89:140-50 pubmed publisher
Nakayama T, Mutsuga N, Tosato G. FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc. Blood. 2007;109:1363-72 pubmed

product information

master code :

MAB716

SKU :

MAB716-100

product name :

Mouse FGFR2 (IIIc) Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Mouse FGFR2 (IIIc) Antibody from R&D Systems is a rat monoclonal antibody to FGFR2. This antibody reacts with bovine,mouse. The Mouse FGFR2 (IIIc) Antibody has been validated for the following applications: Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Western Blot.

target :

FGFR2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

133706

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse FGF R2 alpha (IIIc), Extracellular domains

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Bovine,Mouse

specificity :

Detects IIIc isoforms of mouse FGF R2 in direct ELISAs and Western blots. Does not react with IIIb isoforms of recombinant mouse (rm) FGF R2. In direct ELISAs and Western blots, 100% cross-reactivity with IIIc isoforms of recombinant human (rh) FGF R2 is observed, and no cross-reactivity with IIIb isoforms of rhFGF R2 or any isoforms of rhFGF R1, rmFGF R3, or rhFGF R4 is observed.

gene symbol :

FGFR2

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

FGF R2ss Inhibition of FGF acidic-dependent Cell Proliferation and Neutralization by Rat Anti-Mouse FGF R2 Antibody.

applications :

Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Western Blot

USD :

459 USD

alt names :

BBDS, BEK, BFR-1, CD332, CD332 antigen, CEK3, CFD1, craniofacial dysostosis 1, EC 2.7.10, EC 2.7.10.1, ECT1, FGF R2, fibroblast growth factor receptor 2, FLJ98662, Jackson-Weiss syndrome, JWS, Keratinocyte growth factor receptorreceptor like 14, KGFR, K-sam, KSAM, soluble FGFR4 variant 4, TK14, TK25

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage