Human B7-H6 Antibody | R&D Systems MAB7144 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human B7-H6 Antibody

catalog :

MAB7144

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

875001

reactivity :

human

application :

ELISA, flow cytometry

more info or order :

R&D Systems product webpage

citations: 7

Reference
Fielding C, Sabberwal P, Williamson J, Greenwood E, Crozier T, Zelek W, et al. SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies. elife. 2022;11: pubmed publisher
Cantoni C, Serra M, Parisi E, Azzarone B, Sementa A, Nasto L, et al. Stromal-like Wilms tumor cells induce human Natural Killer cell degranulation and display immunomodulatory properties towards NK cells. Oncoimmunology. 2021;10:1879530 pubmed publisher
Pesce S, Belgrano V, Greppi M, Carlomagno S, Squillario M, Barla A, et al. Different Features of Tumor-Associated NK Cells in Patients With Low-Grade or High-Grade Peritoneal Carcinomatosis. Front Immunol. 2019;10:1963 pubmed publisher
Anft M, Netter P, Urlaub D, Prager I, Schaffner S, Watzl C. NK cell detachment from target cells is regulated by successful cytotoxicity and influences cytokine production. Cell Mol Immunol. 2020;17:347-355 pubmed publisher
Bjørnsen E, Thiruchelvam Kyle L, Hoelsbrekken S, Henden C, Saether P, Boysen P, et al. B7H6 is a functional ligand for NKp30 in rat and cattle and determines NKp30 reactivity toward human cancer cell lines. Eur J Immunol. 2019;49:54-65 pubmed publisher
Charpak Amikam Y, Kubsch T, Seidel E, Oiknine Djian E, Cavaletto N, Yamin R, et al. Human cytomegalovirus escapes immune recognition by NK cells through the downregulation of B7-H6 by the viral genes US18 and US20. Sci Rep. 2017;7:8661 pubmed publisher
Fielding C, Weekes M, Nobre L, Růcková E, Wilkie G, Paulo J, et al. Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation. elife. 2017;6: pubmed publisher

product information

brand :

R&D Systems

master code :

MAB7144

SKU :

MAB7144

product name :

Human B7-H6 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human B7-H6 Antibody from R&D Systems is a mouse monoclonal antibody to B7-H6. This antibody reacts with human. The Human B7-H6 Antibody has been validated for the following applications: Flow Cytometry,ELISA,CyTOF-ready,Knockout Validated.

target :

B7-H6

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

875001

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Flow Cytometry 0.25 ug/10^6 cells, ELISA, CyTOF-ready, Knockout Validated 0.25 ug/10^6 cells

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human B7-H6, Met1-Ser262, Accession # Q68D85

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human B7-H6 in ELISA.

gene symbol :

NCR3LG1

Antibody validation :

Knockout/Knockdown

top caption :

Human B7-H6 Antibody in ELISA Standard Curve.

accessionNumbers :

Q68D85

applications :

ELISA,CyTOF-ready,Knockout Validated,Flow Cytometry

USD :

489 USD

alt names :

B7 homolog 6, B7H6, B7-H6, DKFZp686I21167, DKFZp686O24166, NCR3LG1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage