Mouse FGFR3 Antibody | R&D Systems MAB710 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse FGFR3 Antibody

catalog :

MAB710

quantity :

500 ug (also 25 ug)

price :

569 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

136812

reactivity :

mouse

application :

neutralization, immunohistochemistry - frozen section, blocking or activating experiments

more info or order :

R&D Systems product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; mouse; loading ...; tbl 1	Washausen S, Knabe W. Responses of Epibranchial Placodes to Disruptions of the FGF and BMP Signaling Pathways in Embryonic Mice. Front Cell Dev Biol. 2021;9:712522 pubmed publisher
	Zhang Y, Xu S, Liang K, Li K, Zou Z, Yang C, et al. Neuronal mTORC1 Is Required for Maintaining the Nonreactive State of Astrocytes. J Biol Chem. 2017;292:100-111 pubmed publisher
	Shalhoub V, Ward S, Sun B, Stevens J, Renshaw L, Hawkins N, et al. Fibroblast growth factor 23 (FGF23) and alpha-klotho stimulate osteoblastic MC3T3.E1 cell proliferation and inhibit mineralization. Calcif Tissue Int. 2011;89:140-50 pubmed publisher
	Shin J, Min M, Larrieu Lahargue F, Canron X, Kunstfeld R, Nguyen L, et al. Prox1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: a role for FGF signaling in lymphangiogenesis. Mol Biol Cell. 2006;17:576-84 pubmed

product information

master code :

MAB710

SKU :

MAB710

product name :

Mouse FGFR3 Antibody

unit size :

500 ug (also 25 ug)

description :

The Mouse FGFR3 Antibody from R&D Systems is a rat monoclonal antibody to FGFR3. This antibody reacts with mouse. The Mouse FGFR3 Antibody has been validated for the following applications: Neutralization,Immunohistochemistry-Frozen.

target :

FGFR3

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

136812

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse FGF R3, Glu21-Tyr369 (Asn310Ile, Ala354 del) (predicted), Accession # NP_001156689

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse FGF R3 in direct ELISAs. In direct ELISAs, 100% cross-reactivity with the (IIIb) and (IIIc) isoforms of recombinant human FGF R3 is observed. Neutralizes the bioactivity of mouse FGF R3. Functions equally as well in the neutralization of recombinant mouse (rm) FGF R3 alpha (IIIb) and rmFGF R3 alpha (IIIc).

gene symbol :

FGFR3

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

FGF R3 Inhibition of FGF acidic-dependent Cell Proliferation and Neutral-ization by Mouse FGF R3 Antibody.

accessionNumbers :

NP_001156689

applications :

Neutralization,Immunohistochemistry-Frozen

USD :

569 USD

alt names :

CD333, CEK, EC 2.7.10, FGF R3, fibroblast growth factor receptor 3, HSFGFR3EX, JTK4, JTK4thanatophoric dwarfism

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage