Human Caspase-3 Antibody | R&D Systems MAB707 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Caspase-3 Antibody

catalog :

MAB707

quantity :

100 ug (also 25 ug)

price :

439 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

84803

reactivity :

human, mouse

application :

western blot, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 8

Reference
Yoon Y, Kim C, Kim M, Baik S, Jung P, Eom Y. Interferon-β Overexpression in Adipose Tissue-Derived Stem Cells Induces HepG2 and Macrophage Cell Death in Liver Tumor Organoids via Induction of TNF-Related Apoptosis-Inducing Ligand Expression. Int J Mol Sci. 2024;25: pubmed publisher
Schwarz N, Tumpara S, Wrenger S, Ercetin E, Hamacher J, Welte T, et al. Alpha1-antitrypsin protects lung cancer cells from staurosporine-induced apoptosis: the role of bacterial lipopolysaccharide. Sci Rep. 2020;10:9563 pubmed publisher
Sharp A, Heazell A, Baczyk D, Dunk C, Lacey H, Jones C, et al. Preeclampsia is associated with alterations in the p53-pathway in villous trophoblast. PLoS ONE. 2014;9:e87621 pubmed publisher
Seo K, Kim J, Park J, Song K, Yun E, Park J, et al. PMA synergistically enhances apicularen A-induced cytotoxicity by disrupting microtubule networks in HeLa cells. BMC Cancer. 2014;14:36 pubmed publisher
Ghosh J, Shenoy A, Clark J. Interactions between important regulatory proteins and human alphaB crystallin. Biochemistry. 2007;46:6308-17 pubmed
Choo Wing R, Nedrelow J, Homer R, Elias J, Bhandari V. Developmental differences in the responses of IL-6 and IL-13 transgenic mice exposed to hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2007;293:L142-50 pubmed
Vallon M, Essler M. Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans. J Biol Chem. 2006;281:34179-88 pubmed
You R, Chen M, Wang H, Chou Y, Lin C, Hsieh S. Inhibition of lymphotoxin-beta receptor-mediated cell death by survivin-DeltaEx3. Cancer Res. 2006;66:3051-61 pubmed

product information

master code :

MAB707

SKU :

MAB707

product name :

Human Caspase-3 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human Caspase-3 Antibody from R&D Systems is a mouse monoclonal antibody to Caspase-3. This antibody reacts with human,mouse. The Human Caspase-3 Antibody has been validated for the following applications: ELISA-Based Protein Pin Array,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Knockout Validated.

target :

Caspase-3

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

84803

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human Caspase-3 (18 kDa subunit), aa 29-175, Accession # P42574

isotype :

IgG2b

purity :

Protein A or G purified from ascites

species :

Human,Mouse

specificity :

Detects human precursor Caspase-3 and the 18 kDa subunit generated during apoptosis.

gene symbol :

CASP3

Antibody validation :

Knockout/Knockdown

top caption :

Detection of Human Precursor Caspase-3 and p18 Subunit antibody by Western Blot.

accessionNumbers :

P42574

applications :

ELISA-Based Protein Pin Array,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Knockout Validated

USD :

439 USD

alt names :

Apopain, apoptosis-related cysteine protease, CASP3, CASP-3, caspase 3, apoptosis-related cysteine peptidase, caspase-3, Caspase3, CPP32, CPP-32, CPP32B, CPP32SREBP cleavage activity 1, Cysteine protease CPP32, EC 3.4.22, EC 3.4.22.56, LICE-1, PARP cleavage protease, procaspase3, Protein Yama, SCA-1, Yama

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage