Human Caspase-8 Antibody | R&D Systems MAB704 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Caspase-8 Antibody

catalog :

MAB704

quantity :

100 ug (also 25 ug)

price :

439 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

84131

reactivity :

human

application :

western blot, immunocytochemistry

more info or order :

R&D Systems product webpage

citations: 5

Reference
Hou J, Zhao R, Xia W, Chang C, You Y, Hsu J, et al. PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis. Nat Cell Biol. 2020;22:1264-1275 pubmed publisher
Xu L, Lin X, Zheng Y, Zhou H. Silencing of heat shock protein 27 increases the radiosensitivity of non‑small cell lung carcinoma cells. Mol Med Rep. 2019;20:613-621 pubmed publisher
Mongiat M, Ligresti G, Marastoni S, Lorenzon E, Doliana R, Colombatti A. Regulation of the extrinsic apoptotic pathway by the extracellular matrix glycoprotein EMILIN2. Mol Cell Biol. 2007;27:7176-87 pubmed
Uchida M, Iwase M, Takaoka S, Yoshiba S, Kondo G, Watanabe H, et al. Enhanced susceptibility to tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in oral squamous cell carcinoma cells treated with phosphatidylinositol 3-kinase inhibitors. Int J Oncol. 2007;30:1163-71 pubmed
Raz V, Carlotti F, Vermolen B, van der Poel E, Sloos W, Knaän Shanzer S, et al. Changes in lamina structure are followed by spatial reorganization of heterochromatic regions in caspase-8-activated human mesenchymal stem cells. J Cell Sci. 2006;119:4247-56 pubmed

product information

master code :

MAB704

SKU :

MAB704

product name :

Human Caspase-8 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human Caspase-8 Antibody from R&D Systems is a mouse monoclonal antibody to Caspase-8. This antibody reacts with human. The Human Caspase-8 Antibody has been validated for the following applications: Western Blot,Immunocytochemistry.

target :

Caspase-8

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

84131

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human Caspase-8, aa 234-391

isotype :

IgG2a

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human Caspase-8 precursor in Western blots and a 42ákDa doublet generated during apoptosis.

gene symbol :

CASP8

top caption :

Detection of Human Caspase-8 antibody by Western Blot.

applications :

Western Blot,Immunocytochemistry

USD :

439 USD

alt names :

AIS, androgen receptor, CASP8, Caspase8, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, Mch5, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage