Mouse IL-2 Antibody | R&D Systems MAB702-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse IL-2 Antibody

catalog :

MAB702-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

489 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

JES6-1A12

reactivity :

human, mouse

application :

ELISA, neutralization

more info or order :

R&D Systems product webpage

citations: 16

Reference
Chou C, Hua K, Chen M, Wu C, Hsu C, Wang J, et al. Discovery and characterization of a monoclonal antibody targeting a conformational epitope of IL-6/IL-6Rα to inhibit IL-6/ IL-6Rα/gp130 hexameric signaling complex formation. MAbs. 2022;14:2029675 pubmed publisher
Piao W, Xiong Y, Li L, Saxena V, Smith K, Hippen K, et al. Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration. Cell Rep. 2020;30:1052-1062.e5 pubmed publisher
John B, Naczki C, Patel C, Ghoneum A, Qasem S, Salih Z, et al. Regulation of the bi-directional cross-talk between ovarian cancer cells and adipocytes by SPARC. Oncogene. 2019;38:4366-4383 pubmed publisher
Cao W, Kayama H, Chen M, Delmas A, Sun A, Kim S, et al. The Xenobiotic Transporter Mdr1 Enforces T Cell Homeostasis in the Presence of Intestinal Bile Acids. Immunity. 2017;47:1182-1196.e10 pubmed publisher
Zabala Letona A, Arruabarrena Aristorena A, Martin Martin N, Fernandez Ruiz S, Sutherland J, Clasquin M, et al. mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer. Nature. 2017;547:109-113 pubmed publisher
Hwang I, Kim K, Choi S, Lomunova M. Potentiation of T Cell Stimulatory Activity by Chemical Fixation of a Weak Peptide-MHC Complex. Mol Cells. 2017;40:24-36 pubmed publisher
Mascanfroni I, Takenaka M, Yeste A, Patel B, Wu Y, Kenison J, et al. Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-Î±. Nat Med. 2015;21:638-46 pubmed publisher
Simonetta F, Gestermann N, Bloquet S, Bourgeois C. Interleukin-7 optimizes FOXP3+CD4+ regulatory T cells reactivity to interleukin-2 by modulating CD25 expression. PLoS ONE. 2014;9:e113314 pubmed publisher
Quintana F, Jin H, Burns E, Nadeau M, Yeste A, Kumar D, et al. Aiolos promotes TH17 differentiation by directly silencing Il2 expression. Nat Immunol. 2012;13:770-7 pubmed publisher
Zhang M, Yin L, Zhang K, Sun W, Yang S, Zhang B, et al. Response patterns of cytokines/chemokines in two murine strains after irradiation. Cytokine. 2012;58:169-77 pubmed publisher
Ganesh B, Bhattacharya P, Gopisetty A, Sheng J, Vasu C, Prabhakar B. IL-1? promotes TGF-?1 and IL-2 dependent Foxp3 expression in regulatory T cells. PLoS ONE. 2011;6:e21949 pubmed publisher
Jones G, Stumhofer J, Foster T, Twohig J, Hertzog P, Topley N, et al. Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. FASEB J. 2011;25:409-19 pubmed publisher
Jones G, McLoughlin R, Hammond V, Parker C, Williams J, Malhotra R, et al. Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells. J Immunol. 2010;184:2130-9 pubmed publisher
Ito H, Ando K, Ishikawa T, Nakayama T, Taniguchi M, Saito K, et al. Role of Valpha14+ NKT cells in the development of Hepatitis B virus-specific CTL: activation of Valpha14+ NKT cells promotes the breakage of CTL tolerance. Int Immunol. 2008;20:869-79 pubmed publisher
Muranski P, Boni A, Antony P, Cassard L, Irvine K, Kaiser A, et al. Tumor-specific Th17-polarized cells eradicate large established melanoma. Blood. 2008;112:362-73 pubmed publisher
Bednarski J, Warner R, Rao T, Leonetti F, Yung R, Richardson B, et al. Attenuation of autoimmune disease in Fas-deficient mice by treatment with a cytotoxic benzodiazepine. Arthritis Rheum. 2003;48:757-66 pubmed

product information

master code :

MAB702

SKU :

MAB702-100

product name :

Mouse IL-2 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Mouse IL-2 Antibody from R&D Systems is a rat monoclonal antibody to IL-2. This antibody reacts with mouse. The Mouse IL-2 Antibody has been validated for the following applications: Neutralization,Adoptive Transfer,ELISA Development,ELISpot Development,Luminex Development,ELISA Capture (Matched Antibody Pair).

target :

IL-2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

JES6-1A12

conjugate :

Unconjugated

host :

Rat

immunogen :

E. coli -derived recombinant mouse IL-2

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse IL-2 in ELISAs.

gene symbol :

IL2

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cell Proliferation Induced by IL-2 and Neutralization by Mouse IL-2 Antibody.

applications :

Neutralization,Adoptive Transfer,ELISA Development,ELISpot Development,Luminex Development,ELISA Capture (Matched Antibody Pair)

USD :

489 USD

alt names :

aldesleukin, IL2, IL-2, IL-2lymphokine, interleukin 2, interleukin-2, involved in regulation of T-cell clonal expansion, Proleukin, T cell growth factor, T-cell growth factor, TCGF

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage