product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Phospho-Axl (Y779) Antibody
catalog :
MAB6965
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
713610
reactivity :
human
application :
western blot, immunocytochemistry
more info or order :
R&D Systems product webpage
citations: 5
Reference
Demirsoy S, Tran H, Liu J, Li Y, Yang S, Aregawi D, et al. Targeting Tyro3, Axl, and MerTK Receptor Tyrosine Kinases Significantly Sensitizes Triple-Negative Breast Cancer to CDK4/6 Inhibition. Cancers (Basel). 2024;16: pubmed publisher
Liu C, Harn H, Chen K, Lee J, Lin S, Chiu T. Targeting the Axl and mTOR Pathway Synergizes Immunotherapy and Chemotherapy to Butylidenephthalide in a Recurrent GBM. J Oncol. 2022;2022:3236058 pubmed publisher
Ryan D, Koziol J, ElShamy W. Targeting AXL and RAGE to prevent geminin overexpression-induced triple-negative breast cancer metastasis. Sci Rep. 2019;9:19150 pubmed publisher
Dumas P, Naudin C, Martin Lannerée S, Izac B, Casetti L, Mansier O, et al. Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5- and hypoxia- dependent up-regulation of AXL. Haematologica. 2019;: pubmed publisher
Mori M, Kaneko N, Ueno Y, Yamada M, Tanaka R, Saito R, et al. Gilteritinib, a FLT3/AXL inhibitor, shows antileukemic activity in mouse models of FLT3 mutated acute myeloid leukemia. Invest New Drugs. 2017;35:556-565 pubmed publisher
product information
brand :
R&D Systems
master code :
MAB6965
SKU :
MAB6965
product name :
Human Phospho-Axl (Y779) Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human Phospho-Axl (Y779) Antibody from R&D Systems is a mouse monoclonal antibody to Axl. This antibody reacts with human. The Human Phospho-Axl (Y779) Antibody has been validated for the following applications: Western Blot,Simple Western,Intracellular Staining by Flow Cytometry,Immunocytochemistry,CyTOF-ready.
target :
Axl
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
713610
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.2 ug/mL, Simple Western 4 ug/mL, Intracellular Staining by Flow Cytometry 2.5 ug/10^6 cells, Immunocytochemistry 8-25 ug/mL, CyTOF-ready
host :
Mouse
immunogen :
Phosphopeptide containing the human Axl Y779 site
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Phospho-Axl (Y779) in direct ELISAs and Western blots.
gene symbol :
AXL
top caption :
Detection of Human Phospho-Axl (Y779) antibody by Western Blot.
applications :
Simple Western,Intracellular Staining by Flow Cytometry,Immunocytochemistry,CyTOF-ready,Western Blot
USD :
469 USD
alt names :
AI323647, ARK, AXL oncogene, AXL receptor tyrosine kinase, AXL transforming sequence/gene, EC 2.7.10, EC 2.7.10.1, JTK11, Tyro7, tyrosine-protein kinase receptor UFO, UFO, UFOoncogene AXL
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.