product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human IL-1▀/IL-1F2 Propeptide Antibody
catalog :
MAB6964
quantity :
100 ug (also 25 ug)
price :
439 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
615417
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
R&D Systems product webpage
citations: 8
Reference
de Jong M, Fokkema C, Papazian N, Czeti x, Appelman M, Vermeulen M, et al. An IL-1β-driven neutrophil-stromal cell axis fosters a BAFF-rich protumor microenvironment in individuals with multiple myeloma. Nat Immunol. 2024;25:820-833 pubmed publisher
Guo H, Sun L, Ling S, Xu J. Levistilide A Ameliorates NLRP3 Expression Involving the Syk-p38/JNK Pathway and Peripheral Obliterans in Rats. Mediators Inflamm. 2018;2018:7304096 pubmed publisher
Lendermon E, Coon T, Bednash J, Weathington N, McDyer J, Mallampalli R. Azithromycin decreases NALP3 mRNA stability in monocytes to limit inflammasome-dependent inflammation. Respir Res. 2017;18:131 pubmed publisher
Wang Y, Han Z, Fan Y, Zhang J, Chen K, Gao L, et al. MicroRNA-9 Inhibits NLRP3 Inflammasome Activation in Human Atherosclerosis Inflammation Cell Models through the JAK1/STAT Signaling Pathway. Cell Physiol Biochem. 2017;41:1555-1571 pubmed publisher
Li W, Hua L, Qu P, Yan W, Ming C, Jun Y, et al. NLRP3 inflammasome: a novel link between lipoproteins and atherosclerosis. Arch Med Sci. 2016;12:950-958 pubmed
Wang L, Qu P, Zhao J, Chang Y. NLRP3 and downstream cytokine expression elevated in the monocytes of patients with coronary artery disease. Arch Med Sci. 2014;10:791-800 pubmed publisher
L homme L, Esser N, Riva L, Scheen A, Paquot N, Piette J, et al. Unsaturated fatty acids prevent activation of NLRP3 inflammasome in human monocytes/macrophages. J Lipid Res. 2013;54:2998-3008 pubmed publisher
Qin M, Pirouz A, Kim M, Krutzik S, Garban H, Kim J. Propionibacterium acnes Induces IL-1? secretion via the NLRP3 inflammasome in human monocytes. J Invest Dermatol. 2014;134:381-388 pubmed publisher
product information
master code :
MAB6964
SKU :
MAB6964
product name :
Human IL-1▀/IL-1F2 Propeptide Antibody
unit size :
100 ug (also 25 ug)
description :
The Human IL-1ß/IL-1F2 Propeptide Antibody from R&D Systems is a mouse monoclonal antibody to IL-1 beta/IL-1F2. This antibody reacts with human. The Human IL-1ß/IL-1F2 Propeptide Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Simple Western,Immunocytochemistry.
target :
IL-1 beta/IL-1F2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
615417
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human IL-1▀/IL-1F2 Propeptide, Met1-Asp116, Accession # P01584
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human IL-1▀/IL-1F2 Propeptide in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-1 alpha, rhIL-1F7, rhIL-1F10, rhIL-18, rhIL-36 alpha, rhIL-36 beta, IL-36 gamma, rhIL-36Ra, recombinant mouse IL-1Ra, or the mature peptides of recombinant IL-1 beta from canine, cotton rat, equine, feline, guinea pig, human, mouse, porcine, rabbit, rat, or rhesus is observed.
gene symbol :
IL1B
top caption :
Detection of Human IL-1ss/IL-1F2 Propeptide antibody by Western Blot.
accessionNumbers :
P01584
applications :
Immunohistochemistry,Western Blot,Simple Western,Immunocytochemistry
USD :
439 USD
alt names :
catabolin, IL-1, IL1 beta, IL-1 beta, IL-1b, IL1B, IL1-BETA, IL-1F2, IL1F2IL-1 beta, interleukin 1, beta, interleukin-1 beta, preinterleukin 1 beta, pro-interleukin-1-beta
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.