Human GITR Ligand/TNFSF18 Antibody | R&D Systems MAB6942-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human GITR Ligand/TNFSF18 Antibody

catalog :

MAB6942-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

109114

reactivity :

human

application :

ELISA, neutralization, flow cytometry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 4

Reference
Tuyaerts S, Van Meirvenne S, Bonehill A, Heirman C, Corthals J, Waldmann H, et al. Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells. J Leukoc Biol. 2007;82:93-105 pubmed
Baltz K, Krusch M, Bringmann A, Brossart P, Mayer F, Kloss M, et al. Cancer immunoediting by GITR (glucocorticoid-induced TNF-related protein) ligand in humans: NK cell/tumor cell interactions. FASEB J. 2007;21:2442-54 pubmed
Baumgartner Nielsen J, Vestergaard C, Thestrup Pedersen K, Deleuran M, Deleuran B. Glucocorticoid-induced tumour necrosis factor receptor (GITR) and its ligand (GITRL) in atopic dermatitis. Acta Derm Venereol. 2006;86:393-8 pubmed
Mahesh S, Li Z, Liu B, Fariss R, Nussenblatt R. Expression of GITR ligand abrogates immunosuppressive function of ocular tissue and differentially modulates inflammatory cytokines and chemokines. Eur J Immunol. 2006;36:2128-38 pubmed

product information

brand :

R&D Systems

master code :

MAB6942

SKU :

MAB6942-100

product name :

Human GITR Ligand/TNFSF18 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

seo description :

The Human GITR Ligand/TNFSF18 Antibody from R&D Systems is a mouse monoclonal antibody to GITR Ligand/TNFSF18. This antibody reacts with human. The Human GITR Ligand/TNFSF18 Antibody has been validated for the following applications: ELISA Development,Flow Cytometry,Neutralization,Immunohistochemistry-Frozen,Blockade of Receptor-ligand Interaction,ELISA Capture (Matched Antibody Pair),CyTOF-ready.

target :

GITR Ligand/TNFSF18

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

109114

conjugate :

Unconjugated

dilution :

Flow Cytometry 2.5 ug/10^6 cells, Blockade of Receptor-ligand Interaction, CyTOF-ready, ELISA Capture (Matched Antibody Pair) 2-8 ug/mL

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human GITR Ligand/TNFSF18, Glu52-Ser177, Accession # Q9UNG2

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human GITR Ligand/TNFSF18 in ELISAs. In sandwich immunoassays, no cross-reactivity or interference with recombinant human (rh) APRIL, rhLIGHT, rhTNF-alpha , or rhVEGI is observed.

gene symbol :

TNFSF18

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

accessionNumbers :

Q9UNG2

applications :

Blockade of Receptor-ligand Interaction,ELISA Capture (Matched Antibody Pair),CyTOF-ready,ELISA Development,Flow Cytometry,Immunohistochemistry-Frozen,Neutralization

USD :

469 USD

alt names :

Activation-inducible TNF-related ligand, AITRL, AITRLMGC138237, GITRL, GITRLglucocorticoid-induced TNFR-related protein ligand, Glucocorticoid-induced TNF-related ligand, hGITRLGITR ligand, TL6AITR ligand, TNFSF18, tumor necrosis factor (ligand) superfamily, member 18, tumor necrosis factor ligand superfamily member 18

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage