Human FGFR2 Antibody | R&D Systems MAB684-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human FGFR2 Antibody

catalog :

MAB684-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

98725

reactivity :

human

application :

western blot, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 6

Reference
Jakl V, Popp T, Haupt J, Port M, Roesler R, Wiese S, et al. Effect of Expansion Media on Functional Characteristics of Bone Marrow-Derived Mesenchymal Stromal Cells. Cells. 2023;12: pubmed publisher
Iram T, Kern F, Kaur A, Myneni S, Morningstar A, Shin H, et al. Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17. Nature. 2022;605:509-515 pubmed publisher
Zomerman W, Plasschaert S, Diks S, Lourens H, Meeuwsen de Boer T, Hoving E, et al. Exogenous HGF Bypasses the Effects of ErbB Inhibition on Tumor Cell Viability in Medulloblastoma Cell Lines. PLoS ONE. 2015;10:e0141381 pubmed publisher
Chen G, Qiu H, Ke S, Hu S, Yu S, Zou S. The fibroblast growth factor receptor 2-mediated extracellular signal-regulated kinase 1/2 signaling pathway plays is important in regulating excision repair cross-complementary gene 1 expression in hepatocellular carcinoma. Biomed Rep. 2013;1:604-608 pubmed
Chen G, Qiu H, Ke S, Hu S, Yu S, Zou S. Emodin regulating excision repair cross-complementation group 1 through fibroblast growth factor receptor 2 signaling. World J Gastroenterol. 2013;19:2481-91 pubmed publisher
Ponte A, Marais E, Gallay N, Langonne A, Delorme B, Herault O, et al. The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities. Stem Cells. 2007;25:1737-45 pubmed

product information

master code :

MAB684

SKU :

MAB684-100

product name :

Human FGFR2 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human FGFR2 Antibody from R&D Systems is a mouse monoclonal antibody to FGFR2. This antibody reacts with human. The Human FGFR2 Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Neutralization,CyTOF-ready.

target :

FGFR2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

98725

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human FGF R2 isoforms and Mouse myeloma cell line NS0-derived recombinant human FGF R2 isoforms

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects alpha isoforms (3 Ig-like domains) and ▀ isoforms (2 Ig-like domains) of human FGF R2 in direct ELISAs and Western blots. In direct ELISAs, this antibody reacts with all isoforms of rhFGF R2 but shows approximately a 4-fold preference for (IIIc) isoforms. Approximately 100% cross-reactivity with recombinant mouse FGF R2, 15% cross-reactivity with recombinant human (rh) FGF RI (▀ isoforms), and no cross-reactivity with rhFGF RI ( alpha isoforms), rhFGF R3, or rhFGF R4 is observed.

gene symbol :

FGFR2

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

FGF R2a Inhibition of FGF acidic-dependent Cell Proliferation and Neutralization by Human FGF R2 Antibody.

applications :

Flow Cytometry,Western Blot,Neutralization,CyTOF-ready

USD :

469 USD

alt names :

BBDS, BEK, BFR-1, CD332, CD332 antigen, CEK3, CFD1, craniofacial dysostosis 1, EC 2.7.10, EC 2.7.10.1, ECT1, FGF R2, fibroblast growth factor receptor 2, FLJ98662, Jackson-Weiss syndrome, JWS, Keratinocyte growth factor receptorreceptor like 14, KGFR, K-sam, KSAM, soluble FGFR4 variant 4, TK14, TK25

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage