product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Human RANK/TNFRSF11A Antibody
catalog :
MAB6831-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
80707
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
R&D Systems product webpage
citations: 8
Reference
Passaponti S, Ermini L, Acconci G, Severi F, Romagnoli R, Cutrupi S, et al. Rank-Rankl-Opg Axis in Multiple Sclerosis: The Contribution of Placenta. Cells. 2022;11: pubmed publisher
Gomez R, Tejada M, Rodr xed guez Garc xed a V, Burgu xe9 s O, Santos Llamas A, Mart xed nez Massa A, et al. Histological Grade and Tumor Stage Are Correlated with Expression of Receptor Activator of Nuclear Factor Kappa b (Rank) in Epithelial Ovarian Cancers. Int J Mol Sci. 2022;23: pubmed publisher
Gregori E, Rodríguez García V, Martinez J, Burgues O, Tarín J, Cano A, et al. Differential expression of receptor activator of nuclear factor kappa B in healthy endometrium, ovarian endometrioma, and endometrioid ovarian cancer. Am J Obstet Gynecol. 2020;222:279-281 pubmed publisher
Dimitrakopoulos F, Kottorou A, Antonacopoulou A, Panagopoulos N, Scopa C, Kalofonou M, et al. Expression of Immune System-Related Membrane Receptors CD40, RANK, BAFFR and LTβR is Associated with Clinical Outcome of Operated Non-Small-Cell Lung Cancer Patients. J Clin Med. 2019;8: pubmed publisher
Gomez R, Castro A, Martinez J, Rodríguez García V, Burgues O, Tarín J, et al. Receptor Activator of Nuclear Factor Kappa B (RANK) and Clinicopathological Variables in Endometrial Cancer: A Study at Protein and Gene Level. Int J Mol Sci. 2018;19: pubmed publisher
Day K, Lorenzatti Hiles G, Kozminsky M, Dawsey S, Paul A, Broses L, et al. HER2 and EGFR Overexpression Support Metastatic Progression of Prostate Cancer to Bone. Cancer Res. 2017;77:74-85 pubmed publisher
Li J, Pan Q, Rowan P, Trotter T, Peker D, Regal K, et al. Heparanase promotes myeloma progression by inducing mesenchymal features and motility of myeloma cells. Oncotarget. 2016;7:11299-309 pubmed publisher
Vernal R, Dutzan N, Hernandez M, Chandía S, Puente J, León R, et al. High expression levels of receptor activator of nuclear factor-kappa B ligand associated with human chronic periodontitis are mainly secreted by CD4+ T lymphocytes. J Periodontol. 2006;77:1772-80 pubmed
product information
master code :
MAB6831
SKU :
MAB6831-100
product name :
Human RANK/TNFRSF11A Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Human RANK/TNFRSF11A Antibody from R&D Systems is a mouse monoclonal antibody to RANK/TNFRSF11A. This antibody reacts with human,mouse. The Human RANK/TNFRSF11A Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry.
target :
RANK/TNFRSF11A
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
80707
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human RANK, Leu28-Gly213, Accession # Q9Y6Q6
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects recombinant human RANK in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) 4-1BB, rhBAFF R, recombinant mouse (rm) BAFF R, rhCD27, rhCD30, rhCD40, rhDR3, rhDR4, rhDR5, rhEDAR, rmEDAR, rmFas, rhGITR, rhHVEM, rhLymphotoxin ▀R, rhNGF R, rhOPG, rmRANK, rhRELT, rhTNF RI, rmTNF RI, rhTNF RII, rhTRAIL R2, rhTRAIL R3, rhTRAIL R4, or rhTROY is observed.
gene symbol :
TNFRSF11A
top caption :
RANK/TNFRSF11A antibody in Human Liver by Immunohistochemistry (IHC-P).
accessionNumbers :
Q9Y6Q6
applications :
Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry
USD :
469 USD
alt names :
CD265, CD265 antigen, FEO, loss of heterozygosity, 18, chromosomal region 1, ODFR, ODFROSTS, OFE, OPTB7, Osteoclast differentiation factor receptor, PDB2, RANKLOH18CR1, Receptor activator of NF-KB, receptor activator of nuclear factor-kappa B, TNFRSF11A, TRANCE R, TRANCER, tumor necrosis factor receptor superfamily member 11A, tumor necrosis factor receptor superfamily, member 11a, activator of NFKB, tumor necrosis factor receptor superfamily, member 11a, NFKB activator
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.