This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
RANK/TNFRSF11A Antibody
catalog :
MAB683
quantity :
500 ug
price :
513 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
80704
reactivity :
human
application :
western blot, ELISA, flow cytometry
citations: 9
Reference
Clar K, Weber L, Schmied B, Heitmann J, Marconato M, Tandler C, et al. Receptor Activator of NF-κB (RANK) Confers Resistance to Chemotherapy in AML and Associates with Dismal Disease Course. Cancers (Basel). 2021;13: pubmed publisher
Wang Y, Song Y, Che X, Zhang L, Wang Q, Zhang X, et al. Caveolin‑1 enhances RANKL‑induced gastric cancer cell migration. Oncol Rep. 2018;40:1287-1296 pubmed publisher
Chypre M, Seaman J, Cordeiro O, Willen L, Knoop K, Buchanan A, et al. Characterization and application of two RANK-specific antibodies with different biological activities. Immunol Lett. 2016;171:5-14 pubmed publisher
Schöppl A, Botta A, Prior M, Akgün J, Schuster C, Elbe Bürger A. Langerhans cell precursors acquire RANK/CD265 in prenatal human skin. Acta Histochem. 2015;117:425-30 pubmed publisher
Schmiedel B, Nuebling T, Steinbacher J, Malinovska A, Wende C, Azuma M, et al. Receptor activator for NF-?B ligand in acute myeloid leukemia: expression, function, and modulation of NK cell immunosurveillance. J Immunol. 2013;190:821-31 pubmed publisher
Schmiedel B, Scheible C, Nuebling T, Kopp H, Wirths S, Azuma M, et al. RANKL expression, function, and therapeutic targeting in multiple myeloma and chronic lymphocytic leukemia. Cancer Res. 2013;73:683-94 pubmed publisher
Zhao E, Wang L, Dai J, Kryczek I, Wei S, Vatan L, et al. Regulatory T cells in the bone marrow microenvironment in patients with prostate cancer. Oncoimmunology. 2012;1:152-161 pubmed
Barbaroux J, Beleut M, Brisken C, Mueller C, Groves R. Epidermal receptor activator of NF-kappaB ligand controls Langerhans cells numbers and proliferation. J Immunol. 2008;181:1103-8 pubmed
Vernal R, Dutzan N, Hernandez M, Chandía S, Puente J, León R, et al. High expression levels of receptor activator of nuclear factor-kappa B ligand associated with human chronic periodontitis are mainly secreted by CD4+ T lymphocytes. J Periodontol. 2006;77:1772-80 pubmed
product information
brand :
R&D Systems
master code :
MAB683
SKU :
MAB683
product name :
RANK/TNFRSF11A Antibody
unit size :
500 ug
description :
The Human RANK/TNFRSF11A Antibody from R&D Systems is a mouse monoclonal antibody to RANK/TNFRSF11A. This antibody reacts with human. The Human RANK/TNFRSF11A Antibody has been validated for the following applications: Western Blot, Immunohistochemistry.
target :
RANK/TNFRSF11A
category :
Primary Antibodies
alt names :
CD265, CD265 antigen, FEO, loss of heterozygosity, 18, chromosomal region 1, ODFR, ODFROSTS, OFE, OPTB7, Osteoclast differentiation factor receptor, PDB2, RANKLOH18CR1, Receptor activator of NF-KB, receptor activator of nuclear factor-kappa B, TNFRSF11A, TRANCE R, TRANCER, tumor necrosis factor receptor superfamily member 11A, tumor necrosis factor receptor superfamily, member 11a, activator of NFKB, tumor necrosis factor receptor superfamily, member 11a, NFKB activator
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
80704
conjugate :
Unconjugated
all available conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human RANK/TNFRSF11A. extracellular domain
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human RANK/TNFRSF11A in ELISAs and Western blots
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
gene symbol :
TNFRSF11A
accessionNumbers :
Q9Y6Q6
applications :
Western Blot, Flow Cytometry, CyTOF-ready, ELISA Capture (Matched Antibody Pair)
extended description :
Clone 80704 was used by HLDA to establish CD designation
USD :
475
Jul-22 :
513 USD
product details :
Clone 80704 was used by HLDA to establish CD designation
sizes available :
500 ug (also 25 ug)
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.