Human/Primate CCL5/RANTES Antibody | R&D Systems MAB678 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Primate CCL5/RANTES Antibody

catalog :

MAB678

quantity :

100 ug (also 25 ug, 500 ug)

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

21418

reactivity :

human

application :

western blot, ELISA, neutralization

citations: 26

Published Application/Species/Sample/Dilution	Reference
ELISA; human; loading ...; tbl s7	Bouhaddou M, Memon D, Meyer B, White K, Rezelj V, Correa Marrero M, et al. The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Cell. 2020;182:685-712.e19 pubmed publisher
	Arunachalam P, Charles T, Joag V, Bollimpelli V, Scott M, Wimmers F, et al. T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers. Nat Med. 2020;26:932-940 pubmed publisher
	Liao W, Yen H, Liao C, Tseng T, Lan C, Liu C. DSE regulates the malignant characters of hepatocellular carcinoma cells by modulating CCL5/CCR1 axis. Am J Cancer Res. 2019;9:347-362 pubmed
	Auclair S, Liu F, Niu Q, Hou W, Churchyard G, Morgan C, et al. Distinct susceptibility of HIV vaccine vector-induced CD4 T cells to HIV infection. PLoS Pathog. 2018;14:e1006888 pubmed publisher
	Zhang Y, Li Q, Yang X, Fang F, Li J, Wang Y, et al. SPON2 Promotes M1-like Macrophage Recruitment and Inhibits Hepatocellular Carcinoma Metastasis by Distinct Integrin-Rho GTPase-Hippo Pathways. Cancer Res. 2018;78:2305-2317 pubmed publisher
	Urata S, Izumi K, Hiratsuka K, Maolake A, Natsagdorj A, Shigehara K, et al. C-C motif ligand 5 promotes migration of prostate cancer cells in the prostate cancer bone metastasis microenvironment. Cancer Sci. 2018;109:724-731 pubmed publisher
	Zhao S, Jiang Y, Xu N, Li Q, Zhang Q, Wang S, et al. SPARCL1 suppresses osteosarcoma metastasis and recruits macrophages by activation of canonical WNT/?-catenin signaling through stabilization of the WNT-receptor complex. Oncogene. 2017;: pubmed publisher
	Yang Y, Hu S, Liu J, Cui Y, Fan Y, Lv T, et al. CD8+ T cells promote proliferation of benign prostatic hyperplasia epithelial cells under low androgen level via modulation of CCL5/STAT5/CCND1 signaling pathway. Sci Rep. 2017;7:42893 pubmed publisher
	Henry C, Martin S. Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory "FADDosome" Complex upon TRAIL Stimulation. Mol Cell. 2017;65:715-729.e5 pubmed publisher
	Osei Kumah A, Smith R, Clifton V. Maternal and cord plasma cytokine and chemokine profile in pregnancies complicated by asthma. Cytokine. 2008;43:187-93 pubmed publisher
	Pfleger C, Kaas A, Hansen L, Alizadeh B, Hougaard P, Holl R, et al. Relation of circulating concentrations of chemokine receptor CCR5 ligands to C-peptide, proinsulin and HbA1c and disease progression in type 1 diabetes. Clin Immunol. 2008;128:57-65 pubmed publisher
	Gonzalez R, Seurynck Servoss S, Crowley S, Brown M, Omenn G, Hayes D, et al. Development and validation of sandwich ELISA microarrays with minimal assay interference. J Proteome Res. 2008;7:2406-14 pubmed publisher
	Biancotto A, Iglehart S, Lisco A, Vanpouille C, Grivel J, Lurain N, et al. Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo. AIDS Res Hum Retroviruses. 2008;24:453-62 pubmed publisher
	Qui H, Ferrell E, Nolan N, Phelps B, Tabibiazar R, Whitney D, et al. Fluorescence single-molecule counting assays for high-sensitivity detection of cytokines and chemokines. Clin Chem. 2007;53:2010-2 pubmed
	Aldinucci D, Lorenzon D, Cattaruzza L, Pinto A, Gloghini A, Carbone A, et al. Expression of CCR5 receptors on Reed-Sternberg cells and Hodgkin lymphoma cell lines: involvement of CCL5/Rantes in tumor cell growth and microenvironmental interactions. Int J Cancer. 2008;122:769-76 pubmed
	Todd J, Freese B, Lu A, Held D, Morey J, Livingston R, et al. Ultrasensitive flow-based immunoassays using single-molecule counting. Clin Chem. 2007;53:1990-5 pubmed
	Grivel J, Elliott J, Lisco A, Biancotto A, Condack C, Shattock R, et al. HIV-1 pathogenesis differs in rectosigmoid and tonsillar tissues infected ex vivo with CCR5- and CXCR4-tropic HIV-1. AIDS. 2007;21:1263-72 pubmed
	Biancotto A, Grivel J, Iglehart S, Vanpouille C, Lisco A, Sieg S, et al. Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1. Blood. 2007;109:4272-9 pubmed
	Tikhonov I, Deetz C, Paca R, Berg S, Lukyanenko V, Lim J, et al. Human Vgamma2Vdelta2 T cells contain cytoplasmic RANTES. Int Immunol. 2006;18:1243-51 pubmed
	Cho M, Min S, Chang S, Kim K, Heo S, Lee S, et al. Transforming growth factor beta 1(TGF-beta1) down-regulates TNFalpha-induced RANTES production in rheumatoid synovial fibroblasts through NF-kappaB-mediated transcriptional repression. Immunol Lett. 2006;105:159-66 pubmed
	Edwards M, Johnson M, Johnston S. Combination therapy: Synergistic suppression of virus-induced chemokines in airway epithelial cells. Am J Respir Cell Mol Biol. 2006;34:616-24 pubmed
	Dioszeghy V, Benlhassan Chahour K, Delache B, Dereuddre Bosquet N, Aubenque C, Gras G, et al. Changes in soluble factor-mediated CD8+ cell-derived antiviral activity in cynomolgus macaques infected with simian immunodeficiency virus SIVmac251: relationship to biological markers of progression. J Virol. 2006;80:236-45 pubmed
	Hurst S, McLoughlin R, Monslow J, Owens S, Morgan L, Fuller G, et al. Secretion of oncostatin M by infiltrating neutrophils: regulation of IL-6 and chemokine expression in human mesothelial cells. J Immunol. 2002;169:5244-51 pubmed
	Hirst S, Hallsworth M, Peng Q, Lee T. Selective induction of eotaxin release by interleukin-13 or interleukin-4 in human airway smooth muscle cells is synergistic with interleukin-1beta and is mediated by the interleukin-4 receptor alpha-chain. Am J Respir Crit Care Med. 2002;165:1161-71 pubmed
	Hurst S, Wilkinson T, McLoughlin R, Jones S, Horiuchi S, Yamamoto N, et al. Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Immunity. 2001;14:705-14 pubmed
	Böttcher M, Jenmalm M, Bjorksten B, Garofalo R. Chemoattractant factors in breast milk from allergic and nonallergic mothers. Pediatr Res. 2000;47:592-7 pubmed

product information

brand :

R&D Systems

master code :

MAB678

SKU :

MAB678-100

product name :

Human/Primate CCL5/RANTES Antibody

description :

The Human/Primate CCL5/RANTES Antibody from R&D Systems is a mouse monoclonal antibody to CCL5/RANTES. This antibody reacts with human, primate. The Human/Primate CCL5/RANTES Antibody has been validated for the following applications: Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair).

target :

CCL5/RANTES

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

21418

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human CCL5/RANTES

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human, Primate

specificity :

Detects human and primate CCL5/RANTES in direct ELISAs and Western blots. When used in combination with the biotinylated anti-human/primate CCL5/RANTES detection antibody (Catalog # BAF278) in sandwich ELISAs, no significant cross-reactivity or interference is observed with recombinant human (rh) ANG, rhCNTF, rh beta-ECGF, rhEGF, mouse (m) EGF, rhEpo, bovine (b) FGF acidic, rhFGF acidic, bFGF basic, rhFGF basic, rhFGF-4, rhG-CSF, rhGM-CSF, recombinant mouse (rm) GM-CSF, rhGRO alpha , rhIFN-gamma , rhIGF-I, rhIGF-II, rhIL-1 alpha , rmIL-1 alpha , rhIL-1 beta , rmIL-1 beta , rhIL-1ra, recombinant rat (rr) IL-1ra, rhIL-2, rhIL-3, rmIL-3, rmIL-4, rhIL-5, rmIL-5, rhIL-6, rmIL-6, rhIL-7, rmIL-7, rhIL-8, rhIL-9, rmIL-9, rhIL-10, rhIL-11, rhLIF, rhMCP-1, rhM-CSF, rhMIP-1 alpha , rmMIP-1 alpha , rhMIP-1 beta , rmMIP-1 beta , rhOSM, human (h) PDGF, pPDGF, rhPDGF-AA, rhPDGF-AB, rhPDGF-BB, rhSCF, rmSCF, rhSLPI, rhTGF-alpha , pTGF-beta 1, hTGF-beta 1, rhTGF-beta 1, pTGF-beta 2, rhTGF-beta 2, recombinant canine TGF-beta 3, rhTGF-beta 3, recombinant amphibian TGF-beta 5, rhTNF-alpha , rmTNF-alpha , or rmTNF-beta .

gene symbol :

CCL5

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB678

applications :

Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

369 USD

alt names :

chemokine (C-C motif) ligand 5, D17S136Enormally T-expressed, and presumably secreted, EoCP, Eosinophil chemotactic cytokine, RANTES, SISd, SIS-delta, small inducible cytokine A5 (RANTES), small inducible cytokine subfamily A (Cys-Cys), member 5, Small-inducible cytokine A5, T cell-specific protein P228, T-cell specific protein p288, TCP228T-cell-specific protein RANTES

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.