product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Primate CCL5/RANTES Antibody
catalog :
MAB678-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
479 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
21418
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, neutralization
more info or order :
citations: 38
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Liao W, Yen H, Liao C, Tseng T, Lan C, Liu C. DSE regulates the malignant characters of hepatocellular carcinoma cells by modulating CCL5/CCR1 axis. Am J Cancer Res. 2019;9:347-362 pubmed
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Qui H, Ferrell E, Nolan N, Phelps B, Tabibiazar R, Whitney D, et al. Fluorescence single-molecule counting assays for high-sensitivity detection of cytokines and chemokines. Clin Chem. 2007;53:2010-2 pubmed
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Aldinucci D, Lorenzon D, Cattaruzza L, Pinto A, Gloghini A, Carbone A, et al. Expression of CCR5 receptors on Reed-Sternberg cells and Hodgkin lymphoma cell lines: involvement of CCL5/Rantes in tumor cell growth and microenvironmental interactions. Int J Cancer. 2008;122:769-76 pubmed
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Todd J, Freese B, Lu A, Held D, Morey J, Livingston R, et al. Ultrasensitive flow-based immunoassays using single-molecule counting. Clin Chem. 2007;53:1990-5 pubmed
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Grivel J, Elliott J, Lisco A, Biancotto A, Condack C, Shattock R, et al. HIV-1 pathogenesis differs in rectosigmoid and tonsillar tissues infected ex vivo with CCR5- and CXCR4-tropic HIV-1. AIDS. 2007;21:1263-72 pubmed
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Biancotto A, Grivel J, Iglehart S, Vanpouille C, Lisco A, Sieg S, et al. Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1. Blood. 2007;109:4272-9 pubmed
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Tikhonov I, Deetz C, Paca R, Berg S, Lukyanenko V, Lim J, et al. Human Vgamma2Vdelta2 T cells contain cytoplasmic RANTES. Int Immunol. 2006;18:1243-51 pubmed
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Cho M, Min S, Chang S, Kim K, Heo S, Lee S, et al. Transforming growth factor beta 1(TGF-beta1) down-regulates TNFalpha-induced RANTES production in rheumatoid synovial fibroblasts through NF-kappaB-mediated transcriptional repression. Immunol Lett. 2006;105:159-66 pubmed
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Edwards M, Johnson M, Johnston S. Combination therapy: Synergistic suppression of virus-induced chemokines in airway epithelial cells. Am J Respir Cell Mol Biol. 2006;34:616-24 pubmed
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Dioszeghy V, Benlhassan Chahour K, Delache B, Dereuddre Bosquet N, Aubenque C, Gras G, et al. Changes in soluble factor-mediated CD8+ cell-derived antiviral activity in cynomolgus macaques infected with simian immunodeficiency virus SIVmac251: relationship to biological markers of progression. J Virol. 2006;80:236-45 pubmed
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Saeed R, Varma S, Peng Nemeroff T, Sherry B, Balakhaneh D, Huston J, et al. Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation. J Exp Med. 2005;201:1113-23 pubmed
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Hurst S, McLoughlin R, Monslow J, Owens S, Morgan L, Fuller G, et al. Secretion of oncostatin M by infiltrating neutrophils: regulation of IL-6 and chemokine expression in human mesothelial cells. J Immunol. 2002;169:5244-51 pubmed
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Hirst S, Hallsworth M, Peng Q, Lee T. Selective induction of eotaxin release by interleukin-13 or interleukin-4 in human airway smooth muscle cells is synergistic with interleukin-1beta and is mediated by the interleukin-4 receptor alpha-chain. Am J Respir Crit Care Med. 2002;165:1161-71 pubmed
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Hurst S, Wilkinson T, McLoughlin R, Jones S, Horiuchi S, Yamamoto N, et al. Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Immunity. 2001;14:705-14 pubmed
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Böttcher M, Jenmalm M, Bjorksten B, Garofalo R. Chemoattractant factors in breast milk from allergic and nonallergic mothers. Pediatr Res. 2000;47:592-7 pubmed
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product information
brand :
R&D Systems
master code :
MAB678
SKU :
MAB678-100
product name :
Human/Primate CCL5/RANTES Antibody
unit size :
100 ug (also 25 ug, 500 ug)
seo description :
The Human/Primate CCL5/RANTES Antibody from R&D Systems is a mouse monoclonal antibody to CCL5/RANTES. This antibody reacts with human,primate,primate - macaca fascicularis (crab-eating monkey or cynomolgus macaque). The Human/Primate CCL5/RANTES Antibody has been validated for the following applications: Neutralization,Bioassay,ELISA Development,ELISA Microarray Development,Luminex Development,Mass Spectometry,Functional Assay,ELISA Capture,Immunocytochemistry,Western Blot,ELISA Capture (Matched Antibody Pair).
target :
CCL5/RANTES
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
21418
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Neutralization, ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
host :
Mouse
immunogen :
E. coli -derived recombinant human CCL5/RANTES
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Primate,Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
specificity :
Detects human and primate CCL5/RANTES in direct ELISAs and Western blots. When used in combination with the biotinylated anti-human/primate CCL5/RANTES detection antibody (Catalog # BAF278) in sandwich ELISAs, no significant cross-reactivity or interference is observed with recombinant human (rh) ANG, rhCNTF, rh▀-ECGF, rhEGF, mouse (m) EGF, rhEpo, bovine (b) FGF acidic, rhFGF acidic, bFGF basic, rhFGF basic, rhFGF-4, rhG-CSF, rhGM-CSF, recombinant mouse (rm) GM-CSF, rhGRO alpha , rhIFN-gamma , rhIGF-I, rhIGF-II, rhIL-1 alpha , rmIL-1 alpha , rhIL-1▀, rmIL-1▀, rhIL-1ra, recombinant rat (rr) IL-1ra, rhIL-2, rhIL-3, rmIL-3, rmIL-4, rhIL-5, rmIL-5, rhIL-6, rmIL-6, rhIL-7, rmIL-7, rhIL-8, rhIL-9, rmIL-9, rhIL-10, rhIL-11, rhLIF, rhMCP-1, rhM-CSF, rhMIP-1 alpha , rmMIP-1 alpha , rhMIP-1▀, rmMIP-1▀, rhOSM, human (h) PDGF, pPDGF, rhPDGF-AA, rhPDGF-AB, rhPDGF-BB, rhSCF, rmSCF, rhSLPI, rhTGF-alpha , pTGF┐▀1, hTGF┐▀1, rhTGF┐▀1, pTGF┐▀2, rhTGF┐▀2, recombinant canine TGF┐▀3, rhTGF┐▀3, recombinant amphibian TGF┐▀5, rhTNF-alpha , rmTNF-alpha , or rmTNF┐▀.
gene symbol :
CCL5
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Human CCL5/RANTES by Functional
applications :
Western Blot,ELISA Capture (Matched Antibody Pair),Bioassay,ELISA Development,ELISA Microarray Development,Luminex Development,Mass Spectometry,Neutralization,Immunocytochemistry,Functional Assay,ELISA Capture
USD :
479 USD
alt names :
chemokine (C-C motif) ligand 5, D17S136Enormally T-expressed, and presumably secreted, EoCP, Eosinophil chemotactic cytokine, RANTES, SISd, SIS-delta, small inducible cytokine A5 (RANTES), small inducible cytokine subfamily A (Cys-Cys), member 5, Small-inducible cytokine A5, T cell-specific protein P228, T-cell specific protein p288, TCP228T-cell-specific protein RANTES
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information

R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
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