Human IFN-gamma R1/CD119 Antibody | R&D Systems MAB6731 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IFN-gamma R1/CD119 Antibody

catalog :

MAB6731

quantity :

500 ug (also 25 ug)

price :

599 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

92101

reactivity :

human

application :

western blot, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 13

Reference
Menevse A, Ammer L, Vollmann Zwerenz A, Kupczyk M, Lorenz J, Weidner L, et al. TSPO acts as an immune resistance gene involved in the T cell mediated immune control of glioblastoma. Acta Neuropathol Commun. 2023;11:75 pubmed publisher
Joung J, Kirchgatterer P, Singh A, Cho J, Nety S, Larson R, et al. CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity. Nat Commun. 2022;13:1606 pubmed publisher
Mairpady Shambat S, G xf3 mez Mejia A, Schweizer T, Huemer M, Chang C, Acevedo C, et al. Hyperinflammatory environment drives dysfunctional myeloid cell effector response to bacterial challenge in COVID-19. PLoS Pathog. 2022;18:e1010176 pubmed publisher
Voabil P, de Bruijn M, Roelofsen L, Hendriks S, Brokamp S, van den Braber M, et al. An ex vivo tumor fragment platform to dissect response to PD-1 blockade in cancer. Nat Med. 2021;27:1250-1261 pubmed publisher
Xing Y, Cai J, Qin J, Zhou W, Li C, Li X. Expansion of Monocytic Myeloid-Derived Suppressor Cells in Patients Under Hemodialysis Might Lead to Cardiovascular and Cerebrovascular Events. Front Immunol. 2020;11:577253 pubmed publisher
Szabo P, Levitin H, Miron M, Snyder M, Senda T, Yuan J, et al. Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease. Nat Commun. 2019;10:4706 pubmed publisher
Bin L, Li X, Richers B, Streib J, Hu J, Taylor P, et al. Ankyrin repeat domain 1 regulates innate immune responses against herpes simplex virus 1: A potential role in eczema herpeticum. J Allergy Clin Immunol. 2018;141:2085-2093.e1 pubmed publisher
Xia C, Wolf J, Vijayan M, Studstill C, Ma W, Hahm B. Casein Kinase 1? Mediates the Degradation of Receptors for Type I and Type II Interferons Caused by Hemagglutinin of Influenza A Virus. J Virol. 2018;92: pubmed publisher
Ross S, Sherman M, McElroy P, Lofgren J, Moody G, Baeuerle P, et al. Bispecific T cell engager (BiTE®) antibody constructs can mediate bystander tumor cell killing. PLoS ONE. 2017;12:e0183390 pubmed publisher
Feldhoff L, Rueda C, Moreno Fernandez M, Sauer J, Jackson C, Chougnet C, et al. IL-1? induced HIF-1? inhibits the differentiation of human FOXP3+ T cells. Sci Rep. 2017;7:465 pubmed publisher
Love A, Schwartz I, Petzke M. Induction of indoleamine 2,3-dioxygenase by Borrelia burgdorferi in human immune cells correlates with pathogenic potential. J Leukoc Biol. 2015;97:379-90 pubmed publisher
Nagineni C, Cherukuri K, Kutty V, Detrick B, Hooks J. Interferon-gamma differentially regulates TGF-beta1 and TGF-beta2 expression in human retinal pigment epithelial cells through JAK-STAT pathway. J Cell Physiol. 2007;210:192-200 pubmed
Ebert E, Mehta V. Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription. Cell Immunol. 2006;241:7-13 pubmed

product information

brand :

R&D Systems

master code :

MAB6731

SKU :

MAB6731

product name :

Human IFN-gamma R1/CD119 Antibody

unit size :

500 ug (also 25 ug)

seo description :

The Human IFN-gamma R1/CD119 Antibody from R&D Systems is a mouse monoclonal antibody to IFN-gamma R1/CD119. This antibody reacts with human. The Human IFN-gamma R1/CD119 Antibody has been validated for the following applications: Neutralization,Neutralizing,Flow Cytometry,Western Blot,CyTOF-ready.

target :

IFN-gamma R1/CD119

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

92101

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Flow Cytometry 2.5 ug/10^6 cells, Neutralization 0.01-0.03 ug/mL, CyTOF-ready

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human IFN-gamma R1, Glu18-Gly245, Accession # P15260.1

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human IFN-gamma R1 in direct ELISAs and Western blots. In direct ELISAs, this antibody does not cross-react with recombinant mouse IFN-gamma R1, recombinant human (rh) IFN-gamma R2, or rhIL-10 R▀.

gene symbol :

IFNGR1

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

IFN-? Inhibition of EMCV-induced Cytopathy and Neutralization by Human IFN-? R1/CD119 Antibody.

accessionNumbers :

P15260.1

applications :

CyTOF-ready,Neutralizing,Flow Cytometry,Western Blot,Neutralization

USD :

599 USD

alt names :

AVP, type 2, CD119, CD119 antigen, FLJ45734, IFN-gamma receptor 1, IFNgammaR1, IFN-gamma-R1, IFNGR, IFN-gR1, IFNGR1, immune interferon receptor 1, interferon gamma receptor 1, interferon-gamma receptor alpha chain, type 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage