Human CXCL11/I-TAC Antibody | R&D Systems MAB672 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CXCL11/I-TAC Antibody

catalog :

MAB672

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

87328

reactivity :

human

application :

western blot, ELISA, neutralization, other

citations: 10

Published Application/Species/Sample/Dilution	Reference
other; human; loading ...; fig s1	Shah F, Stepan A, O Mahony A, Velichko S, Folias A, Houle C, et al. Mechanisms of Skin Toxicity Associated with Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators. Cell Chem Biol. 2017;24:858-869.e5 pubmed publisher
	Yuan X, Liu Y, Li G, Lan Z, Ma M, Li H, et al. Blockade of Immune-Checkpoint B7-H4 and Lysine Demethylase 5B in Esophageal Squamous Cell Carcinoma Confers Protective Immunity against P. gingivalis Infection. Cancer Immunol Res. 2019;7:1440-1456 pubmed publisher
	Pinto S, Martinez Romero A, O Connor J, Gil Benso R, San Miguel T, Terrádez L, et al. Intracellular coexpression of CXC- and CC- chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantation. BMC Cancer. 2014;14:118 pubmed publisher
	Oo Y, Weston C, Lalor P, Curbishley S, Withers D, Reynolds G, et al. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J Immunol. 2010;184:2886-98 pubmed publisher
	Yoon K, Park C, You I, Choi H, Lee K, Im S, et al. Expression of CXCL9, -10, -11, and CXCR3 in the tear film and ocular surface of patients with dry eye syndrome. Invest Ophthalmol Vis Sci. 2010;51:643-50 pubmed publisher
	Winter D, Moser J, Kriehuber E, Wiesner C, Knobler R, Trautinger F, et al. Down-modulation of CXCR3 surface expression and function in CD8+ T cells from cutaneous T cell lymphoma patients. J Immunol. 2007;179:4272-82 pubmed
	Curbishley S, Eksteen B, Gladue R, Lalor P, Adams D. CXCR 3 activation promotes lymphocyte transendothelial migration across human hepatic endothelium under fluid flow. Am J Pathol. 2005;167:887-99 pubmed
	Kohrgruber N, Groger M, Meraner P, Kriehuber E, Petzelbauer P, Brandt S, et al. Plasmacytoid dendritic cell recruitment by immobilized CXCR3 ligands. J Immunol. 2004;173:6592-602 pubmed
	Liu L, Jarjour N, Busse W, Kelly E. Enhanced generation of helper T type 1 and 2 chemokines in allergen-induced asthma. Am J Respir Crit Care Med. 2004;169:1118-24 pubmed
	Lasagni L, Francalanci M, Annunziato F, Lazzeri E, Giannini S, Cosmi L, et al. An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4. J Exp Med. 2003;197:1537-49 pubmed

product information

brand :

R&D Systems

master code :

MAB672

SKU :

MAB672-100

product name :

Human CXCL11/I-TAC Antibody

description :

The Human CXCL11/I-TAC Antibody from R&D Systems is a mouse monoclonal antibody to CXCL11/I-TAC. This antibody reacts with human. The Human CXCL11/I-TAC Antibody has been validated for the following applications: Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair).

target :

CXCL11/I-TAC

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

87328

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human CXCL11/I-TAC, Phe22-Phe94, Accession # O14625

isotype :

IgG2a

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human CXCL11/I-TAC in ELISAs and Western blots. In ELISAs, this antibody does not cross-react with recombinant human (rh) CXCL5, 7, 8, 9, or 10. In Western blots, this antibody shows less than 1% cross-reactivity with rhCXCL1, 2, 3, 5, 6, 7, IL-8/CXCL8, 9, 10, 13, CXCL12/SDF-1 alpha , CXCL12/SDF-1 beta , rmCXCL1, 2, 6, 9, 10, CXCL12/SDF-1 alpha , rmCXCL13, rrCXCL1, CXCL3/CINC-2 alpha , CXCL3/CINC-2 beta , or rpIL-8/CXCL8.

gene symbol :

CXCL11

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB672

accessionNumbers :

O14625

applications :

Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

359 USD

alt names :

beta-R1, b-R1, chemokine (C-X-C motif) ligand 11, H174, H174IP9, Interferon gamma-inducible protein 9, Interferon-inducible T-cell alpha chemoattractant, IP-9member 11, ITAC, I-TAC, I-TACMGC102770, SCYB9B, small inducible cytokine subfamily B (Cys-X-Cys), member 9B, Small-inducible cytokine B11

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.