product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse NG2/MCSP Antibody
catalog :
MAB6689
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
546930
reactivity :
mouse
application :
immunohistochemistry, immunocytochemistry
more info or order :
citations: 14
Reference
González Galofre Z, Kilpatrick A, Marques M, S xe1 da Bandeira D, Ventura T, Gomez Salazar M, et al. Runx1+ vascular smooth muscle cells are essential for hematopoietic stem and progenitor cell development in vivo. Nat Commun. 2024;15:1653 pubmed publisher
Chao A, Matak P, Pegram K, Powers J, Hutson C, Jo R, et al. 20-αHydroxycholesterol, an oxysterol in human breast milk, reverses mouse neonatal white matter injury through Gli-dependent oligodendrogenesis. Cell Stem Cell. 2023;30:1054-1071.e8 pubmed publisher
Aue A, Englert N, Harrer L, Schwiering F, Gaab A, K xf6 nig P, et al. NO-sensitive guanylyl cyclase discriminates pericyte-derived interstitial from intra-alveolar myofibroblasts in murine pulmonary fibrosis. Respir Res. 2023;24:167 pubmed publisher
Oliveira D, Coupland K, Shao W, Jin S, Del Gaudio F, Wang S, et al. Active immunotherapy reduces NOTCH3 deposition in brain capillaries in a CADASIL mouse model. EMBO Mol Med. 2023;15:e16556 pubmed publisher
Bretheau F, Castellanos Molina A, B xe9 langer D, Kusik M, Mailhot B, Boisvert A, et al. The alarmin interleukin-1α triggers secondary degeneration through reactive astrocytes and endothelium after spinal cord injury. Nat Commun. 2022;13:5786 pubmed publisher
S xe1 da Bandeira D, Kilpatrick A, Marques M, Gomez Salazar M, Ventura T, Gonzalez Z, et al. PDGFRβ+ cells play a dual role as hematopoietic precursors and niche cells during mouse ontogeny. Cell Rep. 2022;40:111114 pubmed publisher
Nadeem T, Bogue W, Bigit B, Cuervo H. Deficiency of Notch signaling in pericytes results in arteriovenous malformations. JCI Insight. 2020;5: pubmed publisher
Elitt M, Barbar L, Shick H, Powers B, Maeno Hikichi Y, Madhavan M, et al. Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease. Nature. 2020;585:397-403 pubmed publisher
Buhl E, Djudjaj S, Klinkhammer B, Ermert K, Puelles V, Lindenmeyer M, et al. Dysregulated mesenchymal PDGFR-β drives kidney fibrosis. EMBO Mol Med. 2020;12:e11021 pubmed publisher
Wang J, Li G, Wang B, Han S, Sun X, Jiang Y, et al. Metformin inhibits metastatic breast cancer progression and improves chemosensitivity by inducing vessel normalization via PDGF-B downregulation. J Exp Clin Cancer Res. 2019;38:235 pubmed publisher
Sawaguchi S, Varshney S, Ogawa M, Sakaidani Y, Yagi H, Takeshita K, et al. O-GlcNAc on NOTCH1 EGF repeats regulates ligand-induced Notch signaling and vascular development in mammals. elife. 2017;6: pubmed publisher
Yang N, Zhang W, He T, Xing Y. Silencing of galectin-1 inhibits retinal neovascularization and ameliorates retinal hypoxia in a murine model of oxygen-induced ischemic retinopathy. Exp Eye Res. 2017;159:1-15 pubmed publisher
Quattrocelli M, Giacomazzi G, Broeckx S, Ceelen L, Bolca S, Spaas J, et al. Equine-Induced Pluripotent Stem Cells Retain Lineage Commitment Toward Myogenic and Chondrogenic Fates. Stem Cell Reports. 2016;6:55-63 pubmed publisher
Paez Gonzalez P, Asrican B, Rodriguez E, Kuo C. Identification of distinct ChAT? neurons and activity-dependent control of postnatal SVZ neurogenesis. Nat Neurosci. 2014;17:934-42 pubmed publisher
product information
master code :
MAB6689
SKU :
MAB6689
product name :
Mouse NG2/MCSP Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse NG2/MCSP Antibody from R&D Systems is a rat monoclonal antibody to NG2/MCSP. This antibody reacts with mouse. The Mouse NG2/MCSP Antibody has been validated for the following applications: Immunohistochemistry,Immunocytochemistry.
target :
NG2/MCSP
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
546930
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse NG2/MCSP, Leu1587-Ser2229, Accession # Q8VHY0
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse NG2/MCSP in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human NG2/MCSP/CSPG4 is observed.
gene symbol :
CSPG4
top caption :
NG2/MCSP antibody in Mouse Brain by Immunohistochemistry (IHC-Fr).
accessionNumbers :
Q8VHY0
applications :
Immunohistochemistry,Immunocytochemistry
USD :
499 USD
alt names :
AN2, chondroitin sulfate proteoglycan 4, chondroitin sulfate proteoglycan 4 (melanoma-associated), CSPG4, EC 3.6.3, HMW-MAA, MCSP, MCSPChondroitin sulfate proteoglycan NG2, MCSPG, MCSPGMelanoma chondroitin sulfate proteoglycan, MEL-CSPG, MSK16Melanoma-associated chondroitin sulfate proteoglycan, NG2EC 2.7.8
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.