product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse IL-12/IL-35 p35 Antibody
catalog :
MAB6688
quantity :
100 ug (also 25 ug)
price :
429 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
45806
reactivity :
human, mouse
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
R&D Systems product webpage
citations: 6
Reference
Chen S, Xia J, Zhang Y, Zhan Q. IL35 attenuated LPS-induced acute lung injury by regulating macrophage polarization. Mol Biol Rep. 2022;49:5811-5820 pubmed publisher
Li X, Cui W, Hull L, Wang L, Yu T, Xiao M. IL-18 binding protein (IL-18BP) as a novel radiation countermeasure after radiation exposure in mice. Sci Rep. 2020;10:18674 pubmed publisher
Bello R, Abdullah M, Abd Majid R, Chin V, Abd Rachman Isnadi M, Ibraheem Z, et al. IL35 modulation altered survival, cytokine environment and histopathological consequences during malaria infection in mice. Malar J. 2019;18:434 pubmed publisher
Ye J, Huang Y, Que B, Chang C, Liu W, Hu H, et al. Interleukin-12p35 Knock Out Aggravates Doxorubicin-Induced Cardiac Injury and Dysfunction by Aggravating the Inflammatory Response, Oxidative Stress, Apoptosis and Autophagy in Mice. EBioMedicine. 2018;35:29-39 pubmed publisher
Yang X, Yu X, Wei Y. Lentiviral delivery of novel fusion protein IL12/FasTI for cancer immune/gene therapy. PLoS ONE. 2018;13:e0201100 pubmed publisher
Bettini M, Castellaw A, Lennon G, Burton A, Vignali D. Prevention of autoimmune diabetes by ectopic pancreatic ?-cell expression of interleukin-35. Diabetes. 2012;61:1519-26 pubmed publisher
product information
brand :
R&D Systems
master code :
MAB6688
SKU :
MAB6688
product name :
Mouse IL-12/IL-35 p35 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse IL-12/IL-35 p35 Antibody from R&D Systems is a rat monoclonal antibody to IL-12/IL-35 p35. This antibody reacts with human,mouse. The Mouse IL-12/IL-35 p35 Antibody has been validated for the following applications: Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry.
target :
IL-12/IL-35 p35
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
45806
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Immunohistochemistry 8-25 ug/mL
host :
Rat
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived mouse IL-12/IL-35 p35, Arg23-Ala215, Accession # NP_032377
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects mouse IL-12/IL-35 p35 in direct ELISAs. In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse (rm) IL-12 p35+p40 heterodimer or recombinant rat IL-12 p35 is observed. No cross-reactivity with recombinant human IL-12 p35, rmIL-12 p40, rmIL-23 p19+p40 heterodimer, recombinant canine IL-12 p35+p40 heterodimer, or recombinant feline IL-12 p35+p40 heterodimer is observed.
gene symbol :
Il12a
top caption :
IL-12/IL-35 p35 antibody in Mouse Spleen by Immunohistochemistry (IHC-Fr).
accessionNumbers :
NP_032377
applications :
Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry
USD :
429 USD
alt names :
CLMF, CLMF p35, CLMF1, cytotoxic lymphocyte maturation factor 1, p35, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL12, IL-12, subunit p35, IL12A, IL-12A, IL35 subunit, IL35p35, interleukin 12, p35, interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35), interleukin-12 alpha chain, interleukin-12 subunit alpha, NF cell stimulatory factor chain 1, NFSK, NK cell stimulatory factor chain 1, NKSF1, p35
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.