Human FGFR2 (IIIb) Antibody | R&D Systems MAB665 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human FGFR2 (IIIb) Antibody

catalog :

MAB665

quantity :

500 ug (also 25 ug)

price :

569 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

98707

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization

more info or order :

R&D Systems product webpage

citations: 4

Reference
Lau H, Amirruddin N, Loo L, Chan J, Iich E, Krishnan V, et al. FGFR-mediated ERK1/2 signaling contributes to mesendoderm and definitive endoderm formation in vitro. iScience. 2023;26:107265 pubmed publisher
Brownfield D, de Arce A, Ghelfi E, Gillich A, Desai T, Krasnow M. Alveolar cell fate selection and lifelong maintenance of AT2 cells by FGF signaling. Nat Commun. 2022;13:7137 pubmed publisher
Hille A, Grüger S, Christiansen H, Wolff H, Volkmer B, Lehmann J, et al. Effect of tumour-cell-derived or recombinant keratinocyte growth factor (KGF) on proliferation and radioresponse of human epithelial tumour cells (HNSCC) and normal keratinocytes in vitro. Radiat Environ Biophys. 2010;49:261-70 pubmed publisher
Kosman J, Carmean N, Leaf E, Dyamenahalli K, Bassuk J. Translocation of fibroblast growth factor-10 and its receptor into nuclei of human urothelial cells. J Cell Biochem. 2007;102:769-85 pubmed

product information

master code :

MAB665

SKU :

MAB665

product name :

Human FGFR2 (IIIb) Antibody

unit size :

500 ug (also 25 ug)

description :

The Human FGFR2 (IIIb) Antibody from R&D Systems is a mouse monoclonal antibody to FGFR2. This antibody reacts with human,mouse. The Human FGFR2 (IIIb) Antibody has been validated for the following applications: Immunohistochemistry,Immunocytochemistry,Western Blot,Neutralization.

target :

FGFR2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

98707

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human FGF R2 isoforms and S. frugiperda insect ovarian cell line Sf 21-derived recombinant human FGF R2 isoforms

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human,Mouse

specificity :

Reacts with multiple isoforms of human FGF R2 although it shows a marked preference for human FGF R2 (IIIb) isoforms in some assays as described below. In direct ELISAs, displays a three-fold preference for FGF R2 (IIIb) isoforms over (IIIc) isoforms. Shows approximately 50% cross-reactivity with recombinant mouse (rm) FGF R2 isoforms and no cross-reactivity with any isoforms of recombinant human (rh) FGF R1 or rhFGF R3. In Western blots, shows approximately 25% cross-reactivity with rhFGF R2 (IIIc) isoforms, 100% cross-reactivity with all isoforms of rmFGF R2 and no cross-reactivity with any isoforms of rhFGF RI, rhFGF R3, or rhFGF R4. Neutralizes the bioactivity of rhFGF R2 (IIIb) isoforms.

gene symbol :

FGFR2

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

FGF R2a Inhibition of FGF acidic-dependent Cell Proliferation and Neutralization by Human FGF R2 Antibody.

applications :

Immunohistochemistry,Immunocytochemistry,Western Blot,Neutralization

USD :

569 USD

alt names :

BBDS, BEK, BFR-1, CD332, CD332 antigen, CEK3, CFD1, craniofacial dysostosis 1, EC 2.7.10, EC 2.7.10.1, ECT1, FGF R2, fibroblast growth factor receptor 2, FLJ98662, Jackson-Weiss syndrome, JWS, Keratinocyte growth factor receptorreceptor like 14, KGFR, K-sam, KSAM, soluble FGFR4 variant 4, TK14, TK25

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage