product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human LIGHT/TNFSF14 Antibody
catalog :
MAB664
quantity :
500 ug (also 25 ug)
price :
559 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
115520
reactivity :
human
application :
ELISA, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 4
Reference
Holmes T, Wilson E, Black E, Benest A, Vaz C, Tan B, et al. Licensed human natural killer cells aid dendritic cell maturation via TNFSF14/LIGHT. Proc Natl Acad Sci U S A. 2014;111:E5688-96 pubmed publisher
Wang C, Wen T, Routy J, Bernard N, Sekaly R, Watts T. 4-1BBL induces TNF receptor-associated factor 1-dependent Bim modulation in human T cells and is a critical component in the costimulation-dependent rescue of functionally impaired HIV-specific CD8 T cells. J Immunol. 2007;179:8252-63 pubmed
Kang Y, Kim S, Kang J, Han S, Nam E, Kyung H, et al. LIGHT up-regulated on B lymphocytes and monocytes in rheumatoid arthritis mediates cellular adhesion and metalloproteinase production by synoviocytes. Arthritis Rheum. 2007;56:1106-17 pubmed
Otterdal K, Smith C, Oie E, Pedersen T, Yndestad A, Stang E, et al. Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes. Blood. 2006;108:928-35 pubmed
product information
master code :
MAB664
SKU :
MAB664
product name :
Human LIGHT/TNFSF14 Antibody
unit size :
500 ug (also 25 ug)
description :
The Human LIGHT/TNFSF14 Antibody from R&D Systems is a mouse monoclonal antibody to LIGHT/TNFSF14. This antibody reacts with human. The Human LIGHT/TNFSF14 Antibody has been validated for the following applications: Flow Cytometry,Immunohistochemistry-Paraffin,ELISA Capture (Matched Antibody Pair),CyTOF-ready.
target :
LIGHT/TNFSF14
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
115520
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human LIGHT/TNFSF14, Asp74-Val240, Accession # O43557
isotype :
IgG1
purity :
Protein A or G purified from ascites
species :
Human
specificity :
Detects human LIGHT/TNFSF14 in ELISAs. In sandwich immunoassays, no significant cross-reactivity or interference with recombinant human (rh) Fas Ligand, rhAPRIL, recombinant mouse TRANCE, rhTNF-alpha or rhTRAIL is observed.
gene symbol :
TNFSF14
accessionNumbers :
O43557
applications :
Flow Cytometry,Immunohistochemistry-Paraffin,ELISA Capture (Matched Antibody Pair),CyTOF-ready
extended description :
Clone 115520 was used by HLDA to establish CD designation
USD :
559 USD
product details :
Clone 115520 was used by HLDA to establish CD designation
alt names :
CD258, CD258 antigen, delta transmembrane LIGHT, Herpes virus entry mediator ligand, Herpesvirus entry mediator ligand, HVEM-L, HVEMLherpesvirus entry mediator-ligand, ligand for herpesvirus entry mediator, LIGHTherpesvirus entry mediator A, LTg, TNFSF14, TR2, tumor necrosis factor (ligand) superfamily, member 14, tumor necrosis factor ligand superfamily member 14, tumor necrosis factor receptor-like 2, tumor necrosis factor superfamily member LIGHT
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.