product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse ATG7 Antibody
catalog :
MAB6608
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
683906
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry
more info or order :
citations: 15
Reference
Beillevaire D, Migneault F, Turgeon J, Gingras D, Rimbaud A, Marcoux G, et al. Autolysosomes and caspase-3 control the biogenesis and release of immunogenic apoptotic exosomes. Cell Death Dis. 2022;13:145 pubmed publisher
Thomas A, Samykutty A, Gomez Gutierrez J, Yin W, Egger M, McNally M, et al. Actively Targeted Nanodelivery of Echinomycin Induces Autophagy-Mediated Death in Chemoresistant Pancreatic Cancer In Vivo. Cancers (Basel). 2020;12: pubmed publisher
Pandey K, Yu X, Steinmetz A, Alberini C. Autophagy coupled to translation is required for long-term memory. Autophagy. 2020;: pubmed publisher
Sheng Y, Giri R, Davies J, Schreiber V, Alabbas S, Movva R, et al. A Nucleotide Analog Prevents Colitis-Associated Cancer via Beta-Catenin Independently of Inflammation and Autophagy. Cell Mol Gastroenterol Hepatol. 2021;11:33-53 pubmed publisher
Cui D, Drake J, Wilson R, Shute R, Lewellen B, Zhang M, et al. A novel voluntary weightlifting model in mice promotes muscle adaptation and insulin sensitivity with simultaneous enhancement of autophagy and mTOR pathway. FASEB J. 2020;34:7330-7344 pubmed publisher
Bernard M, Yang B, Migneault F, Turgeon J, Dieudé M, Olivier M, et al. Autophagy drives fibroblast senescence through MTORC2 regulation. Autophagy. 2020;:1-13 pubmed publisher
Jung J, Volk C, Marga C, Navarrete Santos A, Jung M, Rujescu D, et al. Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity. Cell Reprogram. 2019;21:187-199 pubmed publisher
Jung S, Choe S, Woo H, Jeong H, An H, Moon H, et al. Autophagic death of neural stem cells mediates chronic stress-induced decline of adult hippocampal neurogenesis and cognitive deficits. Autophagy. 2019;:1-19 pubmed publisher
Zheng W, Xie W, Yin D, Luo R, Liu M, Guo F. ATG5 and ATG7 induced autophagy interplays with UPR via PERK signaling. Cell Commun Signal. 2019;17:42 pubmed publisher
Qi S, Qian J, Chen F, Zhou P, Yue J, Tang F, et al. Expression of autophagy‑associated proteins in rat dental irreversible pulpitis. Mol Med Rep. 2019;19:2749-2757 pubmed publisher
Thapa P, Romero Arocha S, Chung J, Sant Angelo D, Shapiro V. Histone deacetylase 3 is required for iNKT cell development. Sci Rep. 2017;7:5784 pubmed publisher
Marzetti E, Lorenzi M, Landi F, Picca A, Rosa F, Tanganelli F, et al. Altered mitochondrial quality control signaling in muscle of old gastric cancer patients with cachexia. Exp Gerontol. 2017;87:92-99 pubmed publisher
Laclair K, Donde A, Ling J, Jeong Y, Chhabra R, Martin L, et al. Depletion of TDP-43 decreases fibril and plaque β-amyloid and exacerbates neurodegeneration in an Alzheimer's mouse model. Acta Neuropathol. 2016;132:859-873 pubmed
Yang X, Liang L, Zong C, Lai F, Zhu P, Liu Y, et al. Kupffer cells-dependent inflammation in the injured liver increases recruitment of mesenchymal stem cells in aging mice. Oncotarget. 2016;7:1084-95 pubmed publisher
Bernard M, Dieudé M, Yang B, Hamelin K, Underwood K, Hébert M. Autophagy fosters myofibroblast differentiation through MTORC2 activation and downstream upregulation of CTGF. Autophagy. 2014;10:2193-207 pubmed publisher
product information
brand :
R&D Systems
master code :
MAB6608
SKU :
MAB6608
product name :
Human/Mouse ATG7 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human/Mouse ATG7 Antibody from R&D Systems is a mouse monoclonal antibody to ATG7. This antibody reacts with human,mouse,rat. The Human/Mouse ATG7 Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Immunohistochemistry,Simple Western,Intracellular Staining by Flow Cytometry,Immunocytochemistry,CyTOF-ready.
target :
ATG7
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
683906
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 2 ug/mL, Simple Western 20 ug/mL, Immunohistochemistry 8-25 ug/mL, Intracellular Staining by Flow Cytometry 0.25 ug/10^6 cells, Immunocytochemistry 8-25 ug/mL, CyTOF-ready
host :
Mouse
immunogen :
E. coli -derived recombinant human ATG7, Asn387-Gln570, Accession # O95352
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Rat
specificity :
Detects human ATG7 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human ATG3, 4A, 4B, 5, 10, 12, or 16L1 is observed.
gene symbol :
ATG7
top caption :
Detection of Human ATG7 antibody by Western Blot.
accessionNumbers :
O95352
applications :
Simple Western,Intracellular Staining by Flow Cytometry,Immunocytochemistry,CyTOF-ready,Flow Cytometry,Immunohistochemistry,Western Blot
USD :
469 USD
alt names :
APG7, APG7 autophagy 7-like (S. cerevisiae), APG7L, APG7-LIKE, ATG12-activating enzyme E1 ATG7, ATG7 autophagy related 7 homolog (S. cerevisiae), Autophagy-related protein 7, DKFZp434N0735, GSA7, hAGP7, ubiquitin activating enzyme E1-like protein, Ubiquitin-activating enzyme E1-like protein, ubiquitin-like modifier-activating enzyme ATG7
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.