Human CTGF/CCN2 C-Terminus Antibody | R&D Systems MAB660-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CTGF/CCN2 C-Terminus Antibody

catalog :

MAB660-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

88430

reactivity :

human, mouse

application :

western blot, immunohistochemistry

more info or order :

R&D Systems product webpage

citations: 10

Reference
Chen J, Wang C, Chen M. Curcumin inhibits TGF-β1-induced connective tissue growth factor expression through the interruption of Smad2 signaling in human gingival fibroblasts. J Formos Med Assoc. 2018;117:1115-1123 pubmed publisher
Wang Y, Tatakis D. Human gingiva transcriptome during wound healing. J Clin Periodontol. 2017;44:394-402 pubmed publisher
Rodrigues Pinto R, Berry A, Piper Hanley K, Hanley N, Richardson S, Hoyland J. Spatiotemporal analysis of putative notochordal cell markers reveals CD24 and keratins 8, 18, and 19 as notochord-specific markers during early human intervertebral disc development. J Orthop Res. 2016;34:1327-40 pubmed publisher
Gao W, Cai L, Xu X, Fan J, Xue X, Yan X, et al. Anti-CTGF single-chain variable fragment dimers inhibit human airway smooth muscle (ASM) cell proliferation by down-regulating p-Akt and p-mTOR levels. PLoS ONE. 2014;9:e113980 pubmed publisher
Aldhoon B, Kucera T, Smorodinová N, Martinek J, Melenovsky V, Kautzner J. Associations between cardiac fibrosis and permanent atrial fibrillation in advanced heart failure. Physiol Res. 2013;62:247-55 pubmed
Alfaro M, Deskins D, Wallus M, Dasgupta J, Davidson J, Nanney L, et al. A physiological role for connective tissue growth factor in early wound healing. Lab Invest. 2013;93:81-95 pubmed publisher
Tall E, Bernstein A, Oliver N, Gray J, Masur S. TGF-?-stimulated CTGF production enhanced by collagen and associated with biogenesis of a novel 31-kDa CTGF form in human corneal fibroblasts. Invest Ophthalmol Vis Sci. 2010;51:5002-11 pubmed publisher
Bergestuen D, Gravning J, Haugaa K, Sahakyan L, Aakhus S, Thiis Evensen E, et al. Plasma CCN2/connective tissue growth factor is associated with right ventricular dysfunction in patients with neuroendocrine tumors. BMC Cancer. 2010;10:6 pubmed publisher
Chen P, Wang M, Wu S, Su J, Hong C, Chuang S, et al. CTGF enhances the motility of breast cancer cells via an integrin-alphavbeta3-ERK1/2-dependent S100A4-upregulated pathway. J Cell Sci. 2007;120:2053-65 pubmed
Grønborg M, Kristiansen T, Iwahori A, Chang R, Reddy R, Sato N, et al. Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach. Mol Cell Proteomics. 2006;5:157-71 pubmed

product information

master code :

MAB660

SKU :

MAB660-100

product name :

Human CTGF/CCN2 C-Terminus Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human CTGF/CCN2 C-Terminus Antibody from R&D Systems is a mouse monoclonal antibody to CTGF/CCN2. This antibody reacts with human,mouse. The Human CTGF/CCN2 C-Terminus Antibody has been validated for the following applications: Immunohistochemistry,Bioassay,ELISA Development,Western Blot.

target :

CTGF/CCN2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

88430

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human CTGF, Glu247-Ala349, Accession # NP_001892.1

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human,Mouse

specificity :

Detects human CTGF C-teriminal peptide in direct ELISAs. Does not cross-react with recombinant human (rh) LDGF, rhNOV, rhPDGF, rhPlGF, rhVEGF206, rhVEGF-B186, rhVEGF-C, rhVEGF-D, or rhWISP-1.

gene symbol :

CTGF

top caption :

CTGF/CCN2 antibody in Human Breast Cancer Tissue by Immunohistochemistry (IHC-P).

accessionNumbers :

NP_001892.1

applications :

Immunohistochemistry,Bioassay,ELISA Development,Western Blot

extended description :

C-terminal Peptide

USD :

489 USD

product details :

C-terminal Peptide

alt names :

CCN2, CCN2IGFBP-8, connective tissue growth factor, CTGRP, Fisp12, HCS24, Hypertrophic chondrocyte-specific protein 24, IBP-8, IGF-binding protein 8, IGFBP-8, IGFBP8CCN family member 2, Insulin-like growth factor-binding protein 8, MGC102839, NOV2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage