Human Activin B beta B subunit Antibody | R&D Systems MAB659 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Activin B beta B subunit Antibody

catalog :

MAB659

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

146807

reactivity :

human

application :

western blot, neutralization

citations: 3

Reference
Morabito M, Larcher M, Cavalli F, Foray C, Forget A, Mirabal Ortega L, et al. An autocrine ActivinB mechanism drives TGFβ/Activin signaling in Group 3 medulloblastoma. EMBO Mol Med. 2019;11:e9830 pubmed publisher
Dussiot M, Maciel T, Fricot A, Chartier C, Negre O, Veiga J, et al. An activin receptor IIA ligand trap corrects ineffective erythropoiesis in ?-thalassemia. Nat Med. 2014;20:398-407 pubmed publisher
Kupershmidt L, Amit T, Bar Am O, Youdim M, Blumenfeld Z. The neuroprotective effect of Activin A and B: implication for neurodegenerative diseases. J Neurochem. 2007;103:962-71 pubmed

product information

brand :

R&D Systems

master code :

MAB659

SKU :

MAB659-100

product name :

Human Activin B beta B subunit Antibody

description :

The Human Activin B beta B subunit Antibody from R&D Systems is a mouse monoclonal antibody to Activin B/Inhibin beta B. This antibody reacts with human. The Human Activin B beta B subunit Antibody has been validated for the following applications: Western Blot, Neutralization.

target :

Activin B/Inhibin beta B

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

146807

conjugate :

Unconjugated

host :

Mouse

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant human Activin B, Gly293-Ala407, Accession # Q53T31

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Activin B beta B subunit in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) Inhibin B or rhActivin A is observed. In Western blots, approximately 20% cross-reactivity with rhInhibin B is observed and no cross-reactivity with rhActivin A or recombinant mouse Activin A is observed.

gene symbol :

INHBB

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB659

accessionNumbers :

Q53T31

applications :

Western Blot, Neutralization

2020 USD :

339

2021 USD :

359 USD

alt names :

activin AB beta polypeptide, Activin beta-B chain, INHBB, inhibin beta B chain, inhibin, beta B, inhibin, beta B (activin AB beta polypeptide), Inhibin, beta-2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.