product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human ALCAM/CD166 Antibody
catalog :
MAB6561-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
479 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
105902
reactivity :
human, rat
application :
western blot, ELISA, immunocytochemistry, flow cytometry
more info or order :
citations: 11
Reference
Valentiner U, Knips J, Pries R, Clauditz T, Münscher A, Sauter G, et al. Selectin Binding Sites Are Involved in Cell Adhesive Properties of Head and Neck Squamous Cell Carcinoma. Cancers (Basel). 2019;11: pubmed publisher
Koura S, Salama M, El Hussiny M, Khalil M, Lotfy A, Hassan S, et al. Fluoxetine induces direct inhibitory effects on mesenchymal stem cell‑derived osteoprogenitor cells independent of serotonin concentration. Mol Med Rep. 2019;19:2611-2619 pubmed publisher
Hebron K, Li E, Arnold Egloff S, von Lersner A, Taylor C, Houkes J, et al. Alternative splicing of ALCAM enables tunable regulation of cell-cell adhesion through differential proteolysis. Sci Rep. 2018;8:3208 pubmed publisher
Zocchi M, Camodeca C, Nuti E, Rossello A, Ven xe8 R, Tosetti F, et al. ADAM10 new selective inhibitors reduce NKG2D ligand release sensitizing Hodgkin lymphoma cells to NKG2D-mediated killing. Oncoimmunology. 2016;5:e1123367 pubmed publisher
Williams D, Anastos K, Morgello S, Berman J. JAM-A and ALCAM are therapeutic targets to inhibit diapedesis across the BBB of CD14+CD16+ monocytes in HIV-infected individuals. J Leukoc Biol. 2015;97:401-12 pubmed publisher
Ye M, DU Y, Nie Y, Zhou Z, Cao J, Li Y. Overexpression of activated leukocute cell adhesion molecule in gastric cancer is associated with advanced stages and poor prognosis and miR-9 deregulation. Mol Med Rep. 2015;11:2004-12 pubmed publisher
Hansen A, Freeman T, Arnold S, Starchenko A, Jones Paris C, Gilger M, et al. Elevated ALCAM shedding in colorectal cancer correlates with poor patient outcome. Cancer Res. 2013;73:2955-64 pubmed publisher
Ihnen M, Kress K, Kersten J, Kilic E, Choschzick M, Zander H, et al. Relevance of activated leukocyte cell adhesion molecule (ALCAM) in tumor tissue and sera of cervical cancer patients. BMC Cancer. 2012;12:140 pubmed publisher
von Muhlen M, Brault N, Knudsen S, Jiang S, Manalis S. Label-free biomarker sensing in undiluted serum with suspended microchannel resonators. Anal Chem. 2010;82:1905-10 pubmed publisher
Kulasingam V, Zheng Y, Soosaipillai A, Leon A, Gion M, Diamandis E. Activated leukocyte cell adhesion molecule: a novel biomarker for breast cancer. Int J Cancer. 2009;125:9-14 pubmed publisher
Dalerba P, Dylla S, Park I, Liu R, Wang X, Cho R, et al. Phenotypic characterization of human colorectal cancer stem cells. Proc Natl Acad Sci U S A. 2007;104:10158-63 pubmed
product information
master code :
MAB6561
SKU :
MAB6561-100
product name :
Human ALCAM/CD166 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Human ALCAM/CD166 Antibody from R&D Systems is a mouse monoclonal antibody to ALCAM/CD166. This antibody reacts with human,rat. The Human ALCAM/CD166 Antibody has been validated for the following applications: Immunocytochemistry,ELISA Capture,ELISA Development,Flow Cytometry,Western Blot,ELISA Capture (Matched Antibody Pair),CyTOF-ready.
target :
ALCAM/CD166
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
105902
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human ALCAM/CD166, Trp28-Ala526, Accession # Q13740
isotype :
IgG1
purity :
Protein A or G purified from ascites
species :
Human,Rat
specificity :
Detects human ALCAM/CD166 in Western blots. Shows approximately 50% cross-reactivity with recombinant mouse OCAM and no cross-reactivity with recombinant human (rh) BCAM, rhEpCAM, rhMCAM, or rhNCAM-L1.
gene symbol :
ALCAM
accessionNumbers :
Q13740
applications :
Immunocytochemistry,ELISA Capture,ELISA Development,Flow Cytometry,Western Blot,ELISA Capture (Matched Antibody Pair),CyTOF-ready
USD :
479 USD
alt names :
activated leucocyte cell adhesion molecule, activated leukocyte cell adhesion moleculeFLJ38514, CD166, CD166 antigen, MEMDMGC71733
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.