Human TROP-2 Antibody | R&D Systems MAB650 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human TROP-2 Antibody

catalog :

MAB650

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

77220

reactivity :

human

application :

western blot, flow cytometry

citations: 4

Reference
Hao Y, Zhang D, Guo Y, Fu Z, Yu D, Guan G. miR-488-3p sponged by circ-0000495 and mediated upregulation of TROP2 in head and neck squamous cell carcinoma development. J Cancer. 2020;11:3375-3386 pubmed publisher
Yamaguchi M, Nishii Y, Nakamura K, Aoki H, Hirai S, Uchida H, et al. Development of a sensitive screening method for selecting monoclonal antibodies to be internalized by cells. Biochem Biophys Res Commun. 2014;454:600-3 pubmed publisher
Nakatsukasa M, Kawasaki S, Yamasaki K, Fukuoka H, Matsuda A, Tsujikawa M, et al. Tumor-associated calcium signal transducer 2 is required for the proper subcellular localization of claudin 1 and 7: implications in the pathogenesis of gelatinous drop-like corneal dystrophy. Am J Pathol. 2010;177:1344-55 pubmed publisher
Frederick B, Helfrich B, Coldren C, Zheng D, Chan D, Bunn P, et al. Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma. Mol Cancer Ther. 2007;6:1683-91 pubmed

product information

brand :

R&D Systems

master code :

MAB650

SKU :

MAB650-100

product name :

Human TROP-2 Antibody

description :

The Human TROP-2 Antibody from R&D Systems is a mouse monoclonal antibody to TROP-2. This antibody reacts with human. The Human TROP-2 Antibody has been validated for the following applications: Western Blot, Flow Cytometry, CyTOF-ready.

target :

TROP-2

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

77220

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human TROP-2, His27-Thr274, Accession # P09758

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human TROP-2 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) VCAM-1 or rhICAM-1 is observed.

gene symbol :

TACSTD2

catalog number base :

MAB650

accessionNumbers :

P09758

applications :

Western Blot, Flow Cytometry, CyTOF-ready

2020 USD :

339

2021 USD :

359 USD

alt names :

Cell surface glycoprotein Trop-2, EGP1, EGP-1, epithelial glycoprotein-1, GA733-1, GA733-1GP50, gastrointestinal tumor-associated antigen GA7331, gp50, M1S1cell surface glycoprotein TROP2, Membrane component chromosome 1 surface marker 1, membrane component, chromosome 1, surface marker 1, Pancreatic carcinoma marker protein GA733-1, pancreatic carcinoma marker protein GA7331,40kD glycoprotein, identified by monoclonal GA733, T16, TACSTD2, TROP2, TROP2GA7331, tumor-associated calcium signal transducer 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.