Human TROP-2 Antibody | R&D Systems MAB650-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human TROP-2 Antibody

catalog :

MAB650-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

77220

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

more info or order :

R&D Systems product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human	Pham T, Panda A, Kagawa H, To S, Ertekin C, Georgolopoulos G, et al. Modeling human extraembryonic mesoderm cells using naive pluripotent stem cells. Cell Stem Cell. 2022;29:1346-1365.e10 pubmed publisher
	Zijlmans D, Talon I, Verhelst S, Bendall A, Van Nerum K, Javali A, et al. Integrated multi-omics reveal polycomb repressive complex 2 restricts human trophoblast induction. Nat Cell Biol. 2022;24:858-871 pubmed publisher
	Bouchard G, Garcia Marques F, Karacosta L, Zhang W, Bermudez A, Riley N, et al. Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4-pRB Axis in Fibroblasts at the Invasive Tumor Edge. Cancer Res. 2022;82:648-664 pubmed publisher
	Hao Y, Zhang D, Guo Y, Fu Z, Yu D, Guan G. miR-488-3p sponged by circ-0000495 and mediated upregulation of TROP2 in head and neck squamous cell carcinoma development. J Cancer. 2020;11:3375-3386 pubmed publisher
	Yamaguchi M, Nishii Y, Nakamura K, Aoki H, Hirai S, Uchida H, et al. Development of a sensitive screening method for selecting monoclonal antibodies to be internalized by cells. Biochem Biophys Res Commun. 2014;454:600-3 pubmed publisher
	Nakatsukasa M, Kawasaki S, Yamasaki K, Fukuoka H, Matsuda A, Tsujikawa M, et al. Tumor-associated calcium signal transducer 2 is required for the proper subcellular localization of claudin 1 and 7: implications in the pathogenesis of gelatinous drop-like corneal dystrophy. Am J Pathol. 2010;177:1344-55 pubmed publisher
	Frederick B, Helfrich B, Coldren C, Zheng D, Chan D, Bunn P, et al. Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma. Mol Cancer Ther. 2007;6:1683-91 pubmed

product information

brand :

R&D Systems

master code :

MAB650

SKU :

MAB650-100

product name :

Human TROP-2 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

seo description :

The Human TROP-2 Antibody from R&D Systems is a mouse monoclonal antibody to TROP-2. This antibody reacts with human. The Human TROP-2 Antibody has been validated for the following applications: Immunohistochemistry,Bioassay,Flow Cytometry,Immunoprecipitation,Western Blot,Immunocytochemistry,CyTOF-ready.

target :

TROP-2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

77220

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, CyTOF-ready

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human TROP-2, His27-Thr274, Accession # P09758

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human TROP-2 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) VCAM-1 or rhICAM-1 is observed.

gene symbol :

TACSTD2

top caption :

Detection of TROP-2 antibody in PC-3 Human Cell Line antibody by Flow Cytometry.

accessionNumbers :

P09758

applications :

CyTOF-ready,Bioassay,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunocytochemistry

USD :

479 USD

alt names :

Cell surface glycoprotein Trop-2, EGP1, EGP-1, epithelial glycoprotein-1, GA733-1, GA733-1GP50, gastrointestinal tumor-associated antigen GA7331, gp50, M1S1cell surface glycoprotein TROP2, Membrane component chromosome 1 surface marker 1, membrane component, chromosome 1, surface marker 1, Pancreatic carcinoma marker protein GA733-1, pancreatic carcinoma marker protein GA7331,40kD glycoprotein, identified by monoclonal GA733, T16, TACSTD2, TROP2, TROP2GA7331, tumor-associated calcium signal transducer 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage