Human/Primate IL-15 Antibody | R&D Systems MAB647-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Primate IL-15 Antibody

catalog :

MAB647-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

499 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

34505

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 15

Reference
Haug V, Kollar B, Tasigiorgos S, Endo Y, Kauke M, Safi A, et al. Hypothermic Ex Situ Perfusion of Human Limbs With Acellular Solution for 24 Hours. Transplantation. 2020;104:e260-e270 pubmed publisher
Jiang J, Chen X, An H, Yang B, Zhang F, Cheng X. Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling. Sci Rep. 2016;6:32320 pubmed publisher
Sestak K, Thwin H, Dufour J, Liu D, Alvarez X, Laine D, et al. Supplementation of Reduced Gluten Barley Diet with Oral Prolyl Endopeptidase Effectively Abrogates Enteropathy-Associated Changes in Gluten-Sensitive Macaques. Nutrients. 2016;8: pubmed publisher
Periolo N, Guillen L, Arruvito M, Alegre N, Niveloni S, Hwang J, et al. IL-15 controls T cell functions through its influence on CD30 and OX40 antigens in Celiac Disease. Cytokine. 2014;67:44-51 pubmed publisher
Saghafian Hedengren S, Sohlberg E, Theorell J, Carvalho Queiroz C, Nagy N, Persson J, et al. Epstein-Barr virus coinfection in children boosts cytomegalovirus-induced differentiation of natural killer cells. J Virol. 2013;87:13446-55 pubmed publisher
Han K, Zhu X, Liu B, Jeng E, Kong L, Yovandich J, et al. IL-15:IL-15 receptor alpha superagonist complex: high-level co-expression in recombinant mammalian cells, purification and characterization. Cytokine. 2011;56:804-10 pubmed publisher
Finch D, Midha A, Buchanan C, Cochrane D, Craggs R, Cruwys S, et al. Identification of a potent anti-IL-15 antibody with opposing mechanisms of action in vitro and in vivo. Br J Pharmacol. 2011;162:480-90 pubmed publisher
Biancotto A, Iglehart S, Lisco A, Vanpouille C, Grivel J, Lurain N, et al. Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo. AIDS Res Hum Retroviruses. 2008;24:453-62 pubmed publisher
Pfleger C, Schloot N, ter Veld F. Effect of serum content and diluent selection on assay sensitivity and signal intensity in multiplex bead-based immunoassays. J Immunol Methods. 2008;329:214-8 pubmed
Biancotto A, Grivel J, Iglehart S, Vanpouille C, Lisco A, Sieg S, et al. Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1. Blood. 2007;109:4272-9 pubmed
Rhoton Vlasak A, Chegini N, Hardt N, Williams R. Histological characteristics and altered expression of interleukins (IL) IL-13 and IL-15 in endometria of levonorgestrel users with different uterine bleeding patterns. Fertil Steril. 2005;83:659-65 pubmed
Piskin G, Tursen U, Sylva Steenland R, Bos J, Teunissen M. Clinical improvement in chronic plaque-type psoriasis lesions after narrow-band UVB therapy is accompanied by a decrease in the expression of IFN-gamma inducers -- IL-12, IL-18 and IL-23. Exp Dermatol. 2004;13:764-72 pubmed
Yamasaki S, Maeda M, Ohshima K, Kikuchi M, Otsuka T, Harada M. Growth and apoptosis of human natural killer cell neoplasms: role of interleukin-2/15 signaling. Leuk Res. 2004;28:1023-31 pubmed
Borg C, Jalil A, Laderach D, Maruyama K, Wakasugi H, Charrier S, et al. NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs. Blood. 2004;104:3267-75 pubmed
Searle R, Bromage S, Palmer J, Curry J, Lang A. Human amniotic fluid lacks interleukin-2 and interleukin-15 but can interact with the beta-chain of the interleukin-2 receptor. Immunology. 2000;99:411-7 pubmed

product information

brand :

R&D Systems

master code :

MAB647

SKU :

MAB647-100

product name :

Human/Primate IL-15 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

seo description :

The Human/Primate IL-15 Antibody from R&D Systems is a mouse monoclonal antibody to IL-15. This antibody reacts with human,mouse,primate. The Human/Primate IL-15 Antibody has been validated for the following applications: ELISA Capture,ELISA Development,Luminex Development,Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,ELISA Capture (Matched Antibody Pair).

target :

IL-15

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

34505

conjugate :

Unconjugated

dilution :

Neutralization 0.1-0.2 ug/mL, ELISA Capture (Matched Antibody Pair) 2-8 ug/mL

host :

Mouse

immunogen :

E. coli -derived recombinant human IL-15, Asn49-Ser162, Accession # P40933

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Primate

specificity :

Detects human IL-15 in direct ELISAs and Western blots. In ELISAs, no cross-reactivity with recombinant human (rh) IL-1 alpha , -1▀, -2, -3, -4, -5, -6, -7, -8, -9, rmIL-1 alpha , -1▀, -3, -4, -5, -6, -7, -9, or -13 is observed.

gene symbol :

IL15

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cell Proliferation Induced by IL-15 and Neutralization by Human IL-15 Antibody.

accessionNumbers :

P40933

applications :

ELISA Capture (Matched Antibody Pair),ELISA Development,Luminex Development,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization,Immunocytochemistry

USD :

499 USD

alt names :

IL15, IL-15MGC9721, interleukin 15, interleukin-15

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage