| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; human; 1:300; loading ...; fig 1c
| Han B, Zhou B, Qu Y, Gao B, Xu Y, Chung S, et al. FOXC1-induced non-canonical WNT5A-MMP7 signaling regulates invasiveness in triple-negative breast cancer. Oncogene. 2018;37:1399-1408 pubmed publisher |
- western blot; mouse; loading ...; fig 1a
- western blot; human; loading ...; fig 2d, 3f
| Baarsma H, Skronska Wasek W, Mutze K, Ciolek F, Wagner D, John Schuster G, et al. Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD. J Exp Med. 2017;214:143-163 pubmed publisher |
- immunohistochemistry - frozen section; mouse; fig 1
| Li D, Sinha T, Ajima R, Seo H, Yamaguchi T, Wang J. Spatial regulation of cell cohesion by Wnt5a during second heart field progenitor deployment. Dev Biol. 2016;412:18-31 pubmed publisher |
- western blot; human; fig 1
| Bleckmann A, Conradi L, Menck K, Schmick N, Schubert A, Rietkötter E, et al. β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases. Clin Exp Metastasis. 2016;33:309-23 pubmed publisher |
- western blot; mouse; 1:250; fig 3
| Easter S, Mitchell E, Baxley S, Desmond R, Frost A, Serra R. Wnt5a suppresses tumor formation and redirects tumor phenotype in MMTV-Wnt1 tumors. PLoS ONE. 2014;9:e113247 pubmed publisher |
- western blot; human; 1:5000; fig 2a
| Buttler K, Becker J, Pukrop T, Wilting J. Maldevelopment of dermal lymphatics in Wnt5a-knockout-mice. Dev Biol. 2013;381:365-76 pubmed publisher |
| Barbolina M, Burkhalter R, Stack M. Diverse mechanisms for activation of Wnt signalling in the ovarian tumour microenvironment. Biochem J. 2011;437:1-12 pubmed publisher |
| Zhu M, Gu B, Thomas E, Huang Y, Kim Y, Tao H, et al. A fibronectin gradient remodels mixed-phase mesoderm. Sci Adv. 2024;10:eadl6366 pubmed publisher |
| Shu Z, Fan M, Tu B, Tang Z, Wang H, Li H, et al. The Lin28b/Wnt5a axis drives pancreas cancer through crosstalk between cancer associated fibroblasts and tumor epithelium. Nat Commun. 2023;14:6885 pubmed publisher |
| Nualart F, Cifuentes M, Ram xed rez E, Mart xed nez F, Barahona M, Ferrada L, et al. Hyperglycemia increases SCO-spondin and Wnt5a secretion into the cerebrospinal fluid to regulate ependymal cell beating and glucose sensing. PLoS Biol. 2023;21:e3002308 pubmed publisher |
| Liu X, Bae C, Liu B, Zhang Y, Zhou X, Zhang D, et al. Development of opioid-induced hyperalgesia depends on reactive astrocytes controlled by Wnt5a signaling. Mol Psychiatry. 2023;28:767-779 pubmed publisher |
| Yadav V, Jobe N, Satapathy S, Mohapatra P, Andersson T. Increased MARCKS Activity in BRAF Inhibitor-Resistant Melanoma Cells Is Essential for Their Enhanced Metastatic Behavior Independent of Elevated WNT5A and IL-6 Signaling. Cancers (Basel). 2022;14: pubmed publisher |
| Lee G, Kim Y, Park B, Yim S, Park C, Roh H, et al. YAP-dependent Wnt5a induction in hypertrophic adipocytes restrains adiposity. Cell Death Dis. 2022;13:407 pubmed publisher |
| Guo Y, Pei H, Lu B, Zhang D, Zhao Y, Wu F, et al. Aberrantly expressed Wnt5a in nurse-like cells drives resistance to Venetoclax in chronic lymphocytic leukemia. Cell Death Discov. 2022;8:82 pubmed publisher |
| Maity S, Chakraborty A, Mahata S, Roy S, Das A, Sen M. Wnt5A Signaling Blocks Progression of Experimental Visceral Leishmaniasis. Front Immunol. 2022;13:818266 pubmed publisher |
| Radaszkiewicz T, Nosková M, Gömöryová K, Vondálová Blanárová O, Radaszkiewicz K, Pícková M, et al. RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy. elife. 2021;10: pubmed publisher |
| Kaiser K, Jang A, Kompaníková P, Lun M, Prochazka J, Machon O, et al. MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus. Development. 2021;148: pubmed publisher |
| Shao Y, Zhu F, Zhu S, Bai L. HDAC6 suppresses microRNA-199a transcription and augments HPV-positive cervical cancer progression through Wnt5a upregulation. Int J Biochem Cell Biol. 2021;136:106000 pubmed publisher |
| Dani N, Herbst R, McCabe C, Green G, Kaiser K, Head J, et al. A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021;184:3056-3074.e21 pubmed publisher |
| Douglass S, Fane M, Sanseviero E, Ecker B, Kugel C, Behera R, et al. Myeloid-Derived Suppressor Cells Are a Major Source of Wnt5A in the Melanoma Microenvironment and Depend on Wnt5A for Full Suppressive Activity. Cancer Res. 2021;81:658-670 pubmed publisher |
| Edwards J, Brandimarto J, Hu D, Jeong S, Yucel N, Li L, et al. Noncanonical WNT Activation in Human Right Ventricular Heart Failure. Front Cardiovasc Med. 2020;7:582407 pubmed publisher |
| Choi E, Park H, Kim H, Kim H, Kim I, Jeon S, et al. Wnt5a and Wnt11 as acute respiratory distress syndrome biomarkers for severe acute respiratory syndrome coronavirus 2 patients. Eur Respir J. 2020;56: pubmed publisher |
| Asem M, Young A, Oyama C, Claure De La Zerda A, Liu Y, Yang J, et al. Host Wnt5a Potentiates Microenvironmental Regulation of Ovarian Cancer Metastasis. Cancer Res. 2020;80:1156-1170 pubmed publisher |
| Roberts J, Liu G, Paglia D, Kinter C, Fernandes L, Lorenzo J, et al. Deletion of Wnt5a in osteoclasts results in bone loss through decreased bone formation. Ann N Y Acad Sci. 2020;1463:45-59 pubmed publisher |
| Chen Y, Chen L, Yu J, Ghia E, Choi M, Zhang L, et al. Cirmtuzumab blocks Wnt5a/ROR1 stimulation of NF-κB to repress autocrine STAT3 activation in chronic lymphocytic leukemia. Blood. 2019;134:1084-1094 pubmed publisher |
| Santos J, Mendes Silva L, Afonso V, Martins G, Machado R, Lopes J, et al. Exogenous WNT5A and WNT11 proteins rescue CITED2 dysfunction in mouse embryonic stem cells and zebrafish morphants. Cell Death Dis. 2019;10:582 pubmed publisher |
| Hasan M, Rassenti L, Widhopf G, Yu J, Kipps T. Wnt5a causes ROR1 to complex and activate cortactin to enhance migration of chronic lymphocytic leukemia cells. Leukemia. 2019;33:653-661 pubmed publisher |
| Martin Medina A, Lehmann M, Burgy O, Hermann S, Baarsma H, Wagner D, et al. Increased Extracellular Vesicles Mediate WNT5A Signaling in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2018;198:1527-1538 pubmed publisher |
| Oldoni F, van Capelleveen J, Dalila N, Wolters J, Heeren J, Sinke R, et al. Naturally Occurring Variants in LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) and SR-B1 (Scavenger Receptor Class B Type 1) in Humans. Arterioscler Thromb Vasc Biol. 2018;38:1440-1453 pubmed publisher |
| Zhang H, Qi Y, Geng D, Shi Y, Wang X, Yu R, et al. Expression profile and clinical significance of Wnt signaling in human gliomas. Oncol Lett. 2018;15:610-617 pubmed publisher |
| Huang T, Lee P, Wu M, Huang C, Ko C, Lee Y, et al. Distinct roles and differential expression levels of Wnt5a mRNA isoforms in colorectal cancer cells. PLoS ONE. 2017;12:e0181034 pubmed publisher |
| Menck K, Bleckmann A, Wachter A, Hennies B, Ries L, Schulz M, et al. Characterisation of tumour-derived microvesicles in cancer patients' blood and correlation with clinical outcome. J Extracell Vesicles. 2017;6:1340745 pubmed publisher |
| Vesel M, Rapp J, Feller D, Kiss E, Jaromi L, Meggyes M, et al. ABCB1 and ABCG2 drug transporters are differentially expressed in non-small cell lung cancers (NSCLC) and expression is modified by cisplatin treatment via altered Wnt signaling. Respir Res. 2017;18:52 pubmed publisher |
| Jung H, Byun H, Jee B, Min S, Jeoun U, Lee Y, et al. The Ubiquitin-like with PHD and Ring Finger Domains 1 (UHRF1)/DNA Methyltransferase 1 (DNMT1) Axis Is a Primary Regulator of Cell Senescence. J Biol Chem. 2017;292:3729-3739 pubmed publisher |
| Prasad C, Chaurasiya S, Guilmain W, Andersson T. WNT5A signaling impairs breast cancer cell migration and invasion via mechanisms independent of the epithelial-mesenchymal transition. J Exp Clin Cancer Res. 2016;35:144 pubmed publisher |
| Yu J, Chen L, Cui B, Widhopf G, Shen Z, Wu R, et al. Wnt5a induces ROR1/ROR2 heterooligomerization to enhance leukemia chemotaxis and proliferation. J Clin Invest. 2016;126:585-98 pubmed |
| Fuster J, Zuriaga M, Ngo D, Farb M, Aprahamian T, Yamaguchi T, et al. Noncanonical Wnt signaling promotes obesity-induced adipose tissue inflammation and metabolic dysfunction independent of adipose tissue expansion. Diabetes. 2015;64:1235-48 pubmed publisher |
| MacMillan C, Leong H, Dales D, Robertson A, Lewis J, Chambers A, et al. Stage of breast cancer progression influences cellular response to activation of the WNT/planar cell polarity pathway. Sci Rep. 2014;4:6315 pubmed publisher |
| Linnskog R, Jonsson G, Axelsson L, Prasad C, Andersson T. Interleukin-6 drives melanoma cell motility through p38?-MAPK-dependent up-regulation of WNT5A expression. Mol Oncol. 2014;8:1365-78 pubmed publisher |
| Zhao Y, Wang C, Li R, Hui T, Su Y, Yuan Q, et al. Wnt5a promotes inflammatory responses via nuclear factor ?B (NF-?B) and mitogen-activated protein kinase (MAPK) pathways in human dental pulp cells. J Biol Chem. 2014;289:21028-39 pubmed |
| Popp T, Steinritz D, Breit A, Deppe J, Egea V, Schmidt A, et al. Wnt5a/β-catenin signaling drives calcium-induced differentiation of human primary keratinocytes. J Invest Dermatol. 2014;134:2183-2191 pubmed publisher |
| Yap L, Ahmad M, Zabidi M, Chu T, Chai S, Lee H, et al. Oncogenic effects of WNT5A in Epstein-Barr virus‑associated nasopharyngeal carcinoma. Int J Oncol. 2014;44:1774-80 pubmed publisher |
| Menck K, Klemm F, Gross J, Pukrop T, Wenzel D, Binder C. Induction and transport of Wnt 5a during macrophage-induced malignant invasion is mediated by two types of extracellular vesicles. Oncotarget. 2013;4:2057-66 pubmed |
| Halleskog C, Dijksterhuis J, Kilander M, Becerril Ortega J, Villaescusa J, Lindgren E, et al. Heterotrimeric G protein-dependent WNT-5A signaling to ERK1/2 mediates distinct aspects of microglia proinflammatory transformation. J Neuroinflammation. 2012;9:111 pubmed |
