product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse TOP2B Antibody
catalog :
MAB6348
quantity :
100 ug (also 25 ug)
price :
439 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
681417
reactivity :
human, mouse
application :
western blot, immunocytochemistry, other
more info or order :
R&D Systems product webpage
citations: 4
Published Application/Species/Sample/DilutionReference
  • other; mouse; 1:100; loading ...; fig 8j
  • western blot; mouse; 1:1000; loading ...; fig 8a
Hsu J, Xia W, Hsu Y, Chan L, Yu W, Cha J, et al. STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion. Nat Commun. 2018;9:1908 pubmed publisher
  • immunocytochemistry; human; fig 3
Lee K, Bramley R, Cowell I, Jackson G, Austin C. Proteasomal inhibition potentiates drugs targeting DNA topoisomerase II. Biochem Pharmacol. 2016;103:29-39 pubmed publisher
Magdy T, Jiang Z, Jouni M, Fonoudi H, Lyra Leite D, Jung G, et al. RARG variant predictive of doxorubicin-induced cardiotoxicity identifies a cardioprotective therapy. Cell Stem Cell. 2021;28:2076-2089.e7 pubmed publisher
Oury J, Liu Y, Topf A, Todorovic S, Hoedt E, Preethish Kumar V, et al. MACF1 links Rapsyn to microtubule- and actin-binding proteins to maintain neuromuscular synapses. J Cell Biol. 2019;218:1686-1705 pubmed publisher
product information
master code :
MAB6348
SKU :
MAB6348
product name :
Human/Mouse TOP2B Antibody
unit size :
100 ug (also 25 ug)
description :
The Human/Mouse TOP2B Antibody from R&D Systems is a mouse monoclonal antibody to TOP2B. This antibody reacts with human,mouse. The Human/Mouse TOP2B Antibody has been validated for the following applications: Western Blot,Immunocytochemistry.
target :
TOP2B
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
681417
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human TOP2B, Phe1192-Asp1621, Accession # Q02880
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects human TOP2B in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 75% cross-reactivity with recombinant mouse TOP2B and no cross-reactivity with recombinant human TOP2A is observed.
gene symbol :
TOP2B
top caption :
Detection of Human and Mouse TOP2B antibody by Western Blot.
accessionNumbers :
Q02880
applications :
Western Blot,Immunocytochemistry
USD :
439 USD
alt names :
antigen MLAA-44, DNA topoisomerase 2-beta, DNA topoisomerase II beta, DNA topoisomerase II, 180 kD, DNA topoisomerase II, beta isozyme, EC 5.99.1.3, top2beta, TOPIIB, topo II beta, topoisomerase (DNA) II beta (180kD), topoisomerase (DNA) II beta 180kDa, topoisomerase II beta, topoisomerase IIb, U937 associated antigen
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.