Human CD40/TNFRSF5 Antibody | R&D Systems MAB6322-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CD40/TNFRSF5 Antibody

catalog :

MAB6322-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

499 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

82102

reactivity :

human

application :

western blot, neutralization

more info or order :

R&D Systems product webpage

citations: 9

Reference
Shankar S, Stolp J, Juvet S, Beckett J, Macklin P, Issa F, et al. Ex vivo-expanded human CD19+TIM-1+ regulatory B cells suppress immune responses in vivo and are dependent upon the TIM-1/STAT3 axis. Nat Commun. 2022;13:3121 pubmed publisher
Al Awadhi F, Paul V, Luesch H. Structural Diversity and Anticancer Activity of Marine-Derived Elastase Inhibitors: Key Features and Mechanisms Mediating the Antimetastatic Effects in Invasive Breast Cancer. Chembiochem. 2018;19:815-825 pubmed publisher
Sun C, Feng S, Cao Z, Bei J, Chen Q, Zhao W, et al. Up-Regulated Expression of Matrix Metalloproteinases in Endothelial Cells Mediates Platelet Microvesicle-Induced Angiogenesis. Cell Physiol Biochem. 2017;41:2319-2332 pubmed publisher
Martin Gayo E, Cronin J, Hickman T, Ouyang Z, Lindqvist M, Kolb K, et al. Circulating CXCR5+CXCR3+PD-1lo Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth. JCI Insight. 2017;2:e89574 pubmed publisher
Dietrich C, Candon S, Ruemmele F, Devergne O. A soluble form of IL-27R? is a natural IL-27 antagonist. J Immunol. 2014;192:5382-9 pubmed publisher
Weissmüller S, Semmler L, Kalinke U, Christians S, Muller Berghaus J, Waibler Z. ICOS-LICOS interaction is critically involved in TGN1412-mediated T-cell activation. Blood. 2012;119:6268-77 pubmed publisher
Nagy N, Adori M, Rasul A, Heuts F, Salamon D, Ujvári D, et al. Soluble factors produced by activated CD4+ T cells modulate EBV latency. Proc Natl Acad Sci U S A. 2012;109:1512-7 pubmed publisher
van der Vliet H, Wang R, Yue S, Koon H, Balk S, Exley M. Circulating myeloid dendritic cells of advanced cancer patients result in reduced activation and a biased cytokine profile in invariant NKT cells. J Immunol. 2008;180:7287-93 pubmed
Ettinger R, Sims G, Robbins R, Withers D, Fischer R, Grammer A, et al. IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells. J Immunol. 2007;178:2872-82 pubmed

product information

brand :

R&D Systems

master code :

MAB6322

SKU :

MAB6322-100

product name :

Human CD40/TNFRSF5 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

seo description :

The Human CD40/TNFRSF5 Antibody from R&D Systems is a mouse monoclonal antibody to CD40/TNFRSF5. This antibody reacts with human. The Human CD40/TNFRSF5 Antibody has been validated for the following applications: Western Blot,Neutralization.

target :

CD40/TNFRSF5

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

82102

conjugate :

Unconjugated

dilution :

Western Blot 2 ug/mL, Neutralization 5 ug/mL

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human CD40/TNFRSF5, Glu21-Arg193, Accession # P25942

isotype :

IgG2b

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human CD40 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) 4-1BB, rhBAFF R, rhCD27, rhCD30, rhDR3, rhDR6, rhEDAR, rhFas, rhGITR, rhHVEM, rhNGF R, rhOPG, rhRANK, rhTAJ, rhTNF RI, or rhTNF RII is observed.

gene symbol :

CD40

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cell Proliferation Induced by CD40 Ligand/TNFSF5 and Neutralization by Human CD40/TNFRSF5 Antibody.

accessionNumbers :

P25942

applications :

Western Blot,Neutralization

USD :

499 USD

alt names :

B cell surface antigen CD40, B-cell surface antigen CD40, Bp50B cell-associated molecule, CD40, CD40 antigen, CD40 molecule, TNF receptor superfamily member 5, CD40 type II isoform, CD40L receptor, CDw40, MGC9013, nerve growth factor receptor-related B-lymphocyte activation molecule, p50, TNFRSF5, TNFRSF5CD40 antigen (TNF receptor superfamily member 5), tumor necrosis factor receptor superfamily member 5, tumor necrosis factor receptor superfamily, member 5

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage