Human TRANCE/TNFSF11/RANK L Antibody | R&D Systems MAB626 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human TRANCE/TNFSF11/RANK L Antibody

catalog :

MAB626

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

70525

reactivity :

human

application :

immunohistochemistry, neutralization

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 15 ug/ml; loading ...; fig 6a	Meng Y, Zhou W, Jin L, Liu L, Chang K, Mei J, et al. RANKL-mediated harmonious dialogue between fetus and mother guarantees smooth gestation by inducing decidual M2 macrophage polarization. Cell Death Dis. 2017;8:e3105 pubmed publisher
	Moonen C, de Vries T, Rijkschroeff P, Poubelle P, Nicu E, Loos B. The Possible Role of Neutrophils in the Induction of Osteoclastogenesis. J Immunol Res. 2019;2019:8672604 pubmed publisher
	Amiable N, Tat S, Lajeunesse D, Duval N, Pelletier J, Martel Pelletier J, et al. Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts. Bone. 2009;44:1143-50 pubmed publisher
	Gendron S, Boisvert M, Chetoui N, Aoudjit F. Alpha1beta1 integrin and interleukin-7 receptor up-regulate the expression of RANKL in human T cells and enhance their osteoclastogenic function. Immunology. 2008;125:359-69 pubmed publisher
	Lee N, Smolarz A, Olson S, David O, Reiser J, Kutner R, et al. A potential role for Dkk-1 in the pathogenesis of osteosarcoma predicts novel diagnostic and treatment strategies. Br J Cancer. 2007;97:1552-9 pubmed
	Makrygiannakis D, af Klint E, Catrina S, Botusan I, Klareskog E, Klareskog L, et al. Intraarticular corticosteroids decrease synovial RANKL expression in inflammatory arthritis. Arthritis Rheum. 2006;54:1463-72 pubmed
	Fonseca J, Cortez Dias N, Francisco A, Sobral M, Canhao H, Resende C, et al. Inflammatory cell infiltrate and RANKL/OPG expression in rheumatoid synovium: comparison with other inflammatory arthropathies and correlation with outcome. Clin Exp Rheumatol. 2005;23:185-92 pubmed
	Mandelin J, Li T, Hukkanen M, Liljeström M, Salo J, Santavirta S, et al. Interface tissue fibroblasts from loose total hip replacement prosthesis produce receptor activator of nuclear factor-kappaB ligand, osteoprotegerin, and cathepsin K. J Rheumatol. 2005;32:713-20 pubmed
	da Costa C, Annels N, Faaij C, Forsyth R, Hogendoorn P, Egeler R. Presence of osteoclast-like multinucleated giant cells in the bone and nonostotic lesions of Langerhans cell histiocytosis. J Exp Med. 2005;201:687-93 pubmed

product information

brand :

R&D Systems

master code :

MAB626

SKU :

MAB626-100

product name :

Human TRANCE/TNFSF11/RANK L Antibody

description :

The Human TRANCE/TNFSF11/RANK L Antibody from R&D Systems is a mouse monoclonal antibody to TRANCE/TNFSF11/RANK L. This antibody reacts with human. The Human TRANCE/TNFSF11/RANK L Antibody has been validated for the following applications: Immunohistochemistry, Neutralization.

target :

TRANCE/TNFSF11/RANK L

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

70525

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human TRANCE/TNFSF11/RANK L, Gly136-Asp317 (Ala194Gly), Accession # O14788

isotype :

IgG2b

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human TRANCE/TNFSF11/RANK L in direct ELISAs. No cross-reactivity with recombinant mouse TRANCE is observed.

gene symbol :

TNFSF11

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB626

accessionNumbers :

O14788

applications :

Immunohistochemistry, Neutralization

2020 USD :

339

2021 USD :

359 USD

alt names :

CD254, CD254 antigen, ODF, OPGL, OPGLOPTB2, Osteoclast differentiation factor, Osteoprotegerin ligand, RANK L, RANKL, RANKLreceptor activator of nuclear factor kappa B ligand, Receptor activator of nuclear factor kappa-B ligand, sOdf, TNF-related activation-induced cytokine, TNFSF11, TRANCEODFhRANKL2, tumor necrosis factor (ligand) superfamily, member 11, tumor necrosis factor ligand superfamily member 11

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.