product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human CD25/IL-2R alpha Antibody
catalog :
MAB623-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
459 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
24204
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
more info or order :
citations: 6
Reference
Mo Y, Yue M, Yim L, Zhou R, Yu C, Peng Q, et al. Nicotinamide mononucleotide impacts HIV-1 infection by modulating immune activation in T lymphocytes and humanized mice. EBioMedicine. 2023;98:104877 pubmed publisher
Torrino S, Tiroille V, Dolfi B, Dufies M, Hinault C, Bonesso L, et al. UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling. elife. 2021;10: pubmed publisher
Bell C, Sun Y, Nowak U, Clark J, Howlett S, Pekalski M, et al. Sustained in vivo signaling by long-lived IL-2 induces prolonged increases of regulatory T cells. J Autoimmun. 2015;56:66-80 pubmed publisher
Hu H, Kwun J, Aizenstein B, Knechtle S. Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine. Transplantation. 2009;87:1814-20 pubmed publisher
Akoum A, Al Akoum M, Lemay A, Maheux R, Leboeuf M. Imbalance in the peritoneal levels of interleukin 1 and its decoy inhibitory receptor type II in endometriosis women with infertility and pelvic pain. Fertil Steril. 2008;89:1618-24 pubmed
Wang P, Zhang J, Bian H, Wu P, Kuvelkar R, Kung T, et al. Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptor. Biochem J. 2004;380:425-33 pubmed
product information
brand :
R&D Systems
master code :
MAB623
SKU :
MAB623-100
product name :
Human CD25/IL-2R alpha Antibody
unit size :
100 ug (also 25 ug, 500 ug)
seo description :
The Human CD25/IL-2R alpha Antibody from R&D Systems is a mouse monoclonal antibody to CD25/IL-2R alpha. This antibody reacts with cynomolgus monkey,human,xenograft. The Human CD25/IL-2R alpha Antibody has been validated for the following applications: ELISA Capture,Antibody Array Development,ELISA Development,Western Blot,Immunohistochemistry,ELISA Capture (Matched Antibody Pair),Immunocytochemistry.
target :
CD25/IL-2R alpha
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
24204
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Immunohistochemistry 8-25 ug/mL, Immunocytochemistry 8-25 ug/mL, ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human CD25/IL-2 R alpha , Glu22-Cys213, Accession # P01589
isotype :
IgG1
purity :
Protein A or G purified from ascites
species :
Human,Xenograft
specificity :
Detects human CD25/IL-2 R alpha in ELISAs and Western blots. In Western blots, detects recombinant rat CD25/IL-2 R alpha but no cross-reactivity with recombinant mouse CD25/IL-2 R alpha . In sandwich immunoassays, this antibody does not cross-react or interfere with recombinant human (rh) IL-1 RI, rhIL-1 RII, rhIL-2 R▀, rhIL-3 R alpha , rhIL-4 R, rhIL-5 R alpha , rhIL-5 R▀, rhIL-6 R, or rhgp130.
gene symbol :
IL2RA
top caption :
Detection of Recombinant Human and Rat CD25/IL-2 R alpha antibody by Western Blot.
accessionNumbers :
P01589
applications :
ELISA Capture (Matched Antibody Pair),Immunocytochemistry,Antibody Array Development,ELISA Development,Immunohistochemistry,Western Blot
USD :
459 USD
alt names :
CD25, CD25 antigen, IDDM10, IL-2 R alpha, IL-2 receptor subunit alpha, IL2R, IL2R alpha, IL-2R subunit alpha, IL-2Ra, IL2RA, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.