Human CD40 Ligand/TNFSF5 Antibody | R&D Systems MAB617 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CD40 Ligand/TNFSF5 Antibody

catalog :

MAB617

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

40804

reactivity :

human

application :

western blot, immunohistochemistry, flow cytometry

citations: 4

Reference
Bojadzic D, Chen J, Alcazar O, Buchwald P. Design, Synthesis, and Evaluation of Novel Immunomodulatory Small Molecules Targeting the CD40⁻CD154 Costimulatory Protein-Protein Interaction. Molecules. 2018;23: pubmed publisher
Sun C, Feng S, Cao Z, Bei J, Chen Q, Zhao W, et al. Up-Regulated Expression of Matrix Metalloproteinases in Endothelial Cells Mediates Platelet Microvesicle-Induced Angiogenesis. Cell Physiol Biochem. 2017;41:2319-2332 pubmed publisher
Maniar A, Zhang X, Lin W, Gastman B, Pauza C, Strome S, et al. Human gammadelta T lymphocytes induce robust NK cell-mediated antitumor cytotoxicity through CD137 engagement. Blood. 2010;116:1726-33 pubmed publisher
Liu T, Uemura Y, Suzuki M, Narita Y, Hirata S, Ohyama H, et al. Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells. Eur J Immunol. 2008;38:1012-23 pubmed publisher

product information

brand :

R&D Systems

master code :

MAB617

SKU :

MAB617-100

product name :

Human CD40 Ligand/TNFSF5 Antibody

description :

The Human CD40 Ligand/TNFSF5 Antibody from R&D Systems is a mouse monoclonal antibody to CD40 Ligand/TNFSF5. This antibody reacts with human. The Human CD40 Ligand/TNFSF5 Antibody has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Blockade of Receptor-ligand Interaction, CyTOF-ready.

target :

CD40 Ligand/TNFSF5

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

40804

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human CD40 Ligand/TNFSF5, Leu50-Leu261, Accession # P29965

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human CD40 Ligand/TNFSF5 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) CD27 Ligand, rhCD30 Ligand, or recombinant mouse CD40 Ligand is observed.

gene symbol :

CD40LG

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB617

accessionNumbers :

P29965

applications :

Western Blot, Flow Cytometry, Immunohistochemistry, Blockade of Receptor-ligand Interaction, CyTOF-ready

2020 USD :

339

2021 USD :

359 USD

alt names :

CD154, CD154 antigen, CD40 antigen ligand, CD40 ligand, CD40L, CD40-L, CD40LG, CD40LIGM, gp39, hCD40L, HIGM1, T-B cell-activating molecule, T-BAM, T-cell antigen Gp39, TNF-related activation protein, TNFSF5, TNFSF5IMD3, TRAP, TRAPtumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome), tumor necrosis factor (ligand) superfamily member 5, Tumor necrosis factor ligand superfamily member 5

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.