Human IL-13 R alpha 2 Antibody | R&D Systems MAB614-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-13 R alpha 2 Antibody

catalog :

MAB614-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

83834

reactivity :

human

application :

western blot, flow cytometry

more info or order :

R&D Systems product webpage

citations: 8

Reference
Nagai T, Terada N, Fujii M, Nagata Y, Nakahara K, Mukai S, et al. Identification of the α2 chain of interleukin-13 receptor as a potential biomarker for predicting castration resistance of prostate cancer using patient-derived xenograft models. Cancer Rep (Hoboken). 2023;6:e1701 pubmed publisher
Meng M, Liao H, Zhang B, Pan Y, Kong Y, Liu W, et al. Cigarette smoke extracts induce overexpression of the proto-oncogenic gene interleukin-13 receptor ?2 through activation of the PKA-CREB signaling pathway to trigger malignant transformation of lung vascular endothelial cells and angiogenesis. Cell Signal. 2017;31:15-25 pubmed publisher
Shibasaki N, Yamasaki T, Kanno T, Arakaki R, Sakamoto H, Utsunomiya N, et al. Role of IL13RA2 in Sunitinib Resistance in Clear Cell Renal Cell Carcinoma. PLoS ONE. 2015;10:e0130980 pubmed publisher
Kong S, Sengupta S, Tyler B, Bais A, Ma Q, Doucette S, et al. Suppression of human glioma xenografts with second-generation IL13R-specific chimeric antigen receptor-modified T cells. Clin Cancer Res. 2012;18:5949-60 pubmed publisher
Hsi L, Kundu S, Palomo J, Xu B, Ficco R, Vogelbaum M, et al. Silencing IL-13R?2 promotes glioblastoma cell death via endogenous signaling. Mol Cancer Ther. 2011;10:1149-60 pubmed publisher
He H, Xu J, Nelson P, Marshall F, Chung L, Zhau H, et al. Differential expression of the alpha2 chain of the interleukin-13 receptor in metastatic human prostate cancer ARCaPM cells. Prostate. 2010;70:993-1001 pubmed publisher
Daines M, Tabata Y, Walker B, Chen W, Warrier M, Basu S, et al. Level of expression of IL-13R alpha 2 impacts receptor distribution and IL-13 signaling. J Immunol. 2006;176:7495-501 pubmed
Trieu Y, Wen X, Skinnider B, Bray M, Li Z, Claudio J, et al. Soluble interleukin-13Ralpha2 decoy receptor inhibits Hodgkin's lymphoma growth in vitro and in vivo. Cancer Res. 2004;64:3271-5 pubmed

product information

master code :

MAB614

SKU :

MAB614-100

product name :

Human IL-13 R alpha 2 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human IL-13 R alpha 2 Antibody from R&D Systems is a mouse monoclonal antibody to IL-13R alpha 2. This antibody reacts with human. The Human IL-13 R alpha 2 Antibody has been validated for the following applications: ELISA Development,Flow Cytometry,Western Blot.

target :

IL-13 R alpha 2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

83834

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human IL-13 R alpha 2, Cys22-Leu342, Accession # Q14627

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human IL-13 R alpha 2 in direct ELISAs and Western blots. In Western blots, this antibody shows approximately 5% cross-reactivity with recombinant human (rh) IL-4 R and rhIL-9 R and no cross-reactivity with rhIL-5 R alpha , rhIL-5 R▀, rhIL-13 R alpha 1, or recombinant mouse IL-13 R alpha 2.

gene symbol :

IL13RA2

top caption :

Detection of Human IL-13 Ra2 antibody by Western Blot.

accessionNumbers :

Q14627

applications :

ELISA Development,Flow Cytometry,Western Blot

USD :

469 USD

alt names :

cancer/testis antigen 19, CD213a2, CD213a2 antigen, CT19, IL-13 receptor subunit alpha-2, IL13BP, IL13R, IL-13R, IL13R alpha 2, IL-13R subunit alpha-2, IL13RA2, IL-13RA2, IL-13R-alpha-2, interleukin 13 binding protein, interleukin 13 receptor alpha 2 chain, interleukin 13 receptor, alpha 2, interleukin-13 receptor subunit alpha-2, Interleukin-13-binding protein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage