Mouse GM-CSF R alpha Antibody | R&D Systems MAB6130-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse GM-CSF R alpha Antibody

catalog :

MAB6130-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

698423

reactivity :

human, mouse

application :

western blot, immunocytochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 6

Reference
Kwak T, Wang F, Deng H, Condamine T, Kumar V, Perego M, et al. Distinct Populations of Immune-Suppressive Macrophages Differentiate from Monocytic Myeloid-Derived Suppressor Cells in Cancer. Cell Rep. 2020;33:108571 pubmed publisher
Vandestienne M, Zhang Y, Santos Zas I, Al Rifai R, Joffre J, Giraud A, et al. TREM-1 orchestrates angiotensin II-induced monocyte trafficking and promotes experimental abdominal aortic aneurysm. J Clin Invest. 2021;131: pubmed publisher
Guha P, Gardell J, Darpolor J, Cunetta M, Lima M, Miller G, et al. STAT3 inhibition induces Bax-dependent apoptosis in liver tumor myeloid-derived suppressor cells. Oncogene. 2019;38:533-548 pubmed publisher
Deng W, Yang J, Lin X, Shin J, Gao J, Zhong X. Essential Role of mTORC1 in Self-Renewal of Murine Alveolar Macrophages. J Immunol. 2017;198:492-504 pubmed
Schneider C, Nobs S, Heer A, Hirsch E, Penninger J, Siggs O, et al. Frontline Science: Coincidental null mutation of Csf2rÎ± in a colony of PI3KÎ³-/- mice causes alveolar macrophage deficiency and fatal respiratory viral infection. J Leukoc Biol. 2017;101:367-376 pubmed publisher
Weber G, Chousterman B, Hilgendorf I, Robbins C, Theurl I, Gerhardt L, et al. Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis. J Exp Med. 2014;211:1243-56 pubmed publisher

product information

master code :

MAB6130

SKU :

MAB6130-100

product name :

Mouse GM-CSF R alpha Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Mouse GM-CSF R alpha Antibody from R&D Systems is a rat monoclonal antibody to GM-CSFR alpha. This antibody reacts with mouse. The Mouse GM-CSF R alpha Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Neutralization,Immunocytochemistry,CyTOF-ready.

target :

GM-CSF R alpha

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

698423

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse GM-CSF R alpha , Leu30-Pro327, Accession # Q00941

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse GM-CSF R alpha in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) GM-CSF R alpha or rhGM-CSF R beta is observed.

gene symbol :

CSF2RA

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cell Proliferation Induced by GM-CSF and Neutralization by Mouse GM-CSF Ra Antibody.

accessionNumbers :

Q00941

applications :

Flow Cytometry,Western Blot,Neutralization,Immunocytochemistry,CyTOF-ready

USD :

469 USD

alt names :

CD116, CD116 antigen, CDw116, colony stimulating factor 2 receptor alpha subunit, colony stimulating factor 2 receptor, alpha, low-affinity(granulocyte-macrophage), CSF2R, CSF2RA, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GM-CSF receptor alpha subunit, GMCSFR, GMCSFR alpha, GM-CSFRa, GM-CSF-R-alpha, GMCSFR-alpha, GMR, GMR-alpha, granulocyte-macrophage colony-stimulating factor receptor alpha chain, granulocyte-macrophage colony-stimulating factor receptor subunit alpha, MGC3848, MGC4838

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage