product summary
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company name :
R&D Systems
product type :
antibody
product name :
TGF┐▀2 Antibody
catalog :
MAB612-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
8607
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, neutralization
more info or order :
citations: 10
Reference
Sui Y, Hu W, Zhang W, Li D, Zhu H, You Q, et al. Insights into homeobox B9: a propeller for metastasis in dormant prostate cancer progenitor cells. Br J Cancer. 2021;125:1003-1015 pubmed publisher
de Oliveira R, Tye G, Sampaio L, Shiju T, DeDreu J, Menko A, et al. TGFβ1 and TGFβ2 proteins in corneas with and without stromal fibrosis: Delayed regeneration of apical epithelial growth factor barrier and the epithelial basement membrane in corneas with stromal fibrosis. Exp Eye Res. 2020;:108325 pubmed publisher
Kanaji N, Yokohira M, Watanabe N, Kadowaki N, Bandoh S. Transforming Growth Factor-Beta Produced by Non-small Cell Lung Cancer Cells Contributes to Lung Fibroblast Contractile Phenotype. Anticancer Res. 2018;38:2007-2014 pubmed
Yin S, Fan Y, Zhang H, Zhao Z, Hao Y, Li J, et al. Differential TGF? pathway targeting by miR-122 in humans and mice affects liver cancer metastasis. Nat Commun. 2016;7:11012 pubmed publisher
Riemenschneider M, Hirblinger M, Vollmann Zwerenz A, Hau P, Proescholdt M, Jaschinski F, et al. TGF-ß isoforms in cancer: Immunohistochemical expression and Smad-pathway-activity-analysis in thirteen major tumor types with a critical appraisal of antibody specificity and immunohistochemistry assay validity. Oncotarget. 2015;6:26770-81 pubmed publisher
Badri K, Yue M, Carretero O, Aramgam S, Cao J, Sharkady S, et al. Blood pressure homeostasis is maintained by a P311-TGF-? axis. J Clin Invest. 2013;123:4502-12 pubmed publisher
Tudoran O, Soritau O, Balacescu O, Balacescu L, Braicu C, Rus M, et al. Early transcriptional pattern of angiogenesis induced by EGCG treatment in cervical tumour cells. J Cell Mol Med. 2012;16:520-30 pubmed publisher
Kawahara S, Hata Y, Kita T, Arita R, Miura M, Nakao S, et al. Potent inhibition of cicatricial contraction in proliferative vitreoretinal diseases by statins. Diabetes. 2008;57:2784-93 pubmed publisher
Wen F, Liu X, Kobayashi T, Abe S, Fang Q, Kohyama T, et al. Interferon-gamma inhibits transforming growth factor-beta production in human airway epithelial cells by targeting Smads. Am J Respir Cell Mol Biol. 2004;30:816-22 pubmed
Liu X, Kohyama T, Wang H, Zhu Y, Wen F, Kim H, et al. Th2 cytokine regulation of type I collagen gel contraction mediated by human lung mesenchymal cells. Am J Physiol Lung Cell Mol Physiol. 2002;282:L1049-56 pubmed
product information
master code :
MAB612
SKU :
MAB612-100
product name :
TGF┐▀2 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The TGF¿ß2 Antibody from R&D Systems is a mouse monoclonal antibody to TGF-beta 2. This antibody reacts with human,multi-species,xenograft. The TGF¿ß2 Antibody has been validated for the following applications: ELISA Development,Western Blot,Neutralization,Immunohistochemistry,ELISA Capture (Matched Antibody Pair).
target :
TGF-beta 2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
8607
conjugate :
Unconjugated
host :
Mouse
immunogen :
Porcine TGF┐▀1.2
isotype :
IgG2b
purity :
Protein A or G purified from ascites
species :
Human,Multi-Species,Xenograft
specificity :
Detects TGF┐▀2 from multiple species in ELISAs and Western blots. In ELISAs, no cross-reactivity or interfereence with recombinant human (rh) TGF-alpha , recombinant porcineTGF┐▀1, rhTGF┐▀1, recombinant canine TGF┐▀3, recombinant amphibian TGF┐▀5, rhTGF┐▀ RII, or rhTGF┐▀ RIII is observed.
gene symbol :
TGFB2
top caption :
TGF-ss2 antibody in Human Prostate Cancer by Immunohistochemistry (IHC-P).
applications :
ELISA Development,Western Blot,Neutralization,Immunohistochemistry,ELISA Capture (Matched Antibody Pair)
USD :
469 USD
alt names :
BSC-1 cell growth inhibitor, Cetermin, Glioblastoma-derived T-cell suppressor factor, G-TSF, MGC116892, Polyergin, TGFB2, TGFbeta 2, TGF-beta2, TGF-beta-2, transforming growth factor beta-2, transforming growth factor, beta 2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.