Human IL-12/IL-23 p40 MAb (Clone 169516) | R&D Systems MAB6091-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-12/IL-23 p40 MAb (Clone 169516)

catalog :

MAB6091-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

169516

reactivity :

human

application :

western blot, flow cytometry

more info or order :

R&D Systems product webpage

citations: 5

Reference
Pandya P, Sayers R, Ting J, Morshedian S, Torres C, Cudal J, et al. Integration of phage and yeast display platforms: A reliable and cost effective approach for binning of peptides as displayed on-phage. PLoS ONE. 2020;15:e0233961 pubmed publisher
van Meijgaarden K, Khatri B, Smith S, Drittij A, de Paus R, Goeman J, et al. Cross-laboratory evaluation of multiplex bead assays including independent common reference standards for immunological monitoring of observational and interventional human studies. PLoS ONE. 2018;13:e0201205 pubmed publisher
Fukuda K, Miura Y, Maeda T, Hayashi S, Kurosaka M. Interleukinâ€‘12B is upregulated by decoy receptor 3 in rheumatoid synovial fibroblasts. Mol Med Rep. 2016;13:3647-52 pubmed publisher
Yu R, Gallagher G. A naturally occurring, soluble antagonist of human IL-23 inhibits the development and in vitro function of human Th17 cells. J Immunol. 2010;185:7302-8 pubmed publisher
Vaknin Dembinsky A, Balashov K, Weiner H. IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production. J Immunol. 2006;176:7768-74 pubmed

product information

master code :

MAB6091

SKU :

MAB6091-100

product name :

Human IL-12/IL-23 p40 MAb (Clone 169516)

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human IL-12/IL-23 p40 MAb (Clone 169516) from R&D Systems is a mouse monoclonal antibody to IL-12/IL-23 p40. This antibody reacts with human,yeast. The Human IL-12/IL-23 p40 MAb (Clone 169516) has been validated for the following applications: Western Blot,ELISA Development,Flow Cytometry.

target :

IL-12/IL-23 p40

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

169516

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-23 p19/p40 heterodimer, Ile23-Ser328, Accession # P29460

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Yeast

specificity :

Detects human IL-12/IL-23 p40 subunit in direct ELISAs and Western blots. Recognizes IL-12 and IL-23 heterodimers as well as p40 homodimers. Shows 100% cross-reactivity with porcine IL-12/IL-23 p40 and no cross-reactivity with mouse IL-12/IL-23 p40.

gene symbol :

IL12B

accessionNumbers :

P29460

applications :

ELISA Development,Flow Cytometry,Western Blot

USD :

459 USD

alt names :

CLMF, CLMF p40, CLMF2, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL12 p40, IL-12 subunit p40, IL12B, IL-12B, IL-12BNK cell stimulatory factor chain 2, interleukin 12, p40, interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocytematuration factor 2, p40), interleukin-12 beta chain, interleukin-12 subunit beta, natural killer cell stimulatory factor, 40 kD subunit, NKSF, NKSF2, NKSF2IL12, subunit p40

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage