product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human IL-1▀/IL-1F2 Antibody
catalog :
MAB601-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2805
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization
more info or order :
citations: 64
Reference
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Tarricone E, Mattiuzzo E, Belluzzi E, Elia R, Benetti A, Venerando R, et al. Anti-Inflammatory Performance of Lactose-Modified Chitosan and Hyaluronic Acid Mixtures in an In Vitro Macrophage-Mediated Inflammation Osteoarthritis Model. Cells. 2020;9: pubmed publisher
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Sacre S, Jaxa Chamiec A, Low C, Chamberlain G, Tralau Stewart C. Structural Modification of the Antidepressant Mianserin Suggests That Its Anti-inflammatory Activity May Be Independent of 5-Hydroxytryptamine Receptors. Front Immunol. 2019;10:1167 pubmed publisher
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Dautova Y, Kapustin A, Pappert K, Epple M, Okkenhaug H, Cook S, et al. Calcium phosphate particles stimulate interleukin-1β release from human vascular smooth muscle cells: A role for spleen tyrosine kinase and exosome release. J Mol Cell Cardiol. 2018;115:82-93 pubmed publisher
Reuschl A, Edwards M, Parker R, Connell D, Hoang L, Halliday A, et al. Innate activation of human primary epithelial cells broadens the host response to Mycobacterium tuberculosis in the airways. PLoS Pathog. 2017;13:e1006577 pubmed publisher
Fan Y, Zhang X, Yang L, Wang J, Hu Y, Bian A, et al. Zinc inhibits high glucose-induced NLRP3 inflammasome activation in human peritoneal mesothelial cells. Mol Med Rep. 2017;16:5195-5202 pubmed publisher
Osei E, Florez Sampedro L, Tasena H, Faiz A, Noordhoek J, Timens W, et al. miR-146a-5p plays an essential role in the aberrant epithelial-fibroblast cross-talk in COPD. Eur Respir J. 2017;49: pubmed publisher
Osei E, Noordhoek J, Hackett T, Spanjer A, Postma D, Timens W, et al. Interleukin-1α drives the dysfunctional cross-talk of the airway epithelium and lung fibroblasts in COPD. Eur Respir J. 2016;48:359-69 pubmed publisher
Zhu D, Tang R, Lv L, Wen Y, Liu H, Zhang X, et al. Interleukin-1β mediates high glucose induced phenotypic transition in human aortic endothelial cells. Cardiovasc Diabetol. 2016;15:42 pubmed publisher
Folestad A, xc5 lund M, Asteberg S, Fowelin J, Aurell Y, G xf6 thlin J, et al. Offloading treatment is linked to activation of proinflammatory cytokines and start of bone repair and remodeling in Charcot arthropathy patients. J Foot Ankle Res. 2015;8:72 pubmed publisher
Valentina M, Jan F, Peder N, Bo Z, Hongjie D, Pernille K. Cytokine detection and simultaneous assessment of rheumatoid factor interference in human serum and synovial fluid using high-sensitivity protein arrays on plasmonic gold chips. BMC Biotechnol. 2015;15:73 pubmed publisher
Stoppelkamp S, Veseli K, Stang K, Schlensak C, Wendel H, Walker T. Identification of Predictive Early Biomarkers for Sterile-SIRS after Cardiovascular Surgery. PLoS ONE. 2015;10:e0135527 pubmed publisher
Sommer A, Fabri M. Vitamin D regulates cytokine patterns secreted by dendritic cells to promote differentiation of IL-22-producing T cells. PLoS ONE. 2015;10:e0130395 pubmed publisher
Ghonime M, Mitra S, Eldomany R, Wewers M, Gavrilin M. Inflammasome priming is similar for francisella species that differentially induce inflammasome activation. PLoS ONE. 2015;10:e0127278 pubmed publisher
Rahman M, Mitra S, Sarkar A, Wewers M. Alpha 1-antitrypsin does not inhibit human monocyte caspase-1. PLoS ONE. 2015;10:e0117330 pubmed publisher
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Ghonime M, Shamaa O, Das S, Eldomany R, Fernandes Alnemri T, Alnemri E, et al. Inflammasome priming by lipopolysaccharide is dependent upon ERK signaling and proteasome function. J Immunol. 2014;192:3881-8 pubmed publisher
Verway M, Bouttier M, Wang T, Carrier M, Calderon M, An B, et al. Vitamin D induces interleukin-1? expression: paracrine macrophage epithelial signaling controls M. tuberculosis infection. PLoS Pathog. 2013;9:e1003407 pubmed publisher
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product information
brand :
R&D Systems
master code :
MAB601
SKU :
MAB601-100
product name :
Human IL-1▀/IL-1F2 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
seo description :
The Human IL-1ß/IL-1F2 Antibody from R&D Systems is a mouse monoclonal antibody to IL-1 beta/IL-1F2. This antibody reacts with human,mouse,rat. The Human IL-1ß/IL-1F2 Antibody has been validated for the following applications: Immunocytochemistry,Bioassay,Western Blot,Affinity Chromatography,Antibody Array Development,Array Development,Electrochemiluminescent Assay,ELISA (Capture),ELISA Development,ELISA Development (Capture),Luminex Development,Neutralizing,Neutralization,Immunohistochemistry,Simple Western,ELISA Capture (Matched Antibody Pair).
target :
IL-1 beta/IL-1F2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
2805
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Simple Western 10 ug/mL, Neutralization 0.05-0.2 ug/mL, Immunocytochemistry 8-25 ug/mL, ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
host :
Mouse
immunogen :
E. coli -derived recombinant human IL-1▀/IL-1F2
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Rat
specificity :
Detects human IL-1▀/IL-1F2 in sandwich ELISAs and Western blots. In sandwich ELISAs, less than 4% cross-reactivity with recombinant rat (rr) IL-1▀ and less than 0.1% with recombinant porcine (rp) IL-1▀, recombinant human IL-1 alpha , rpIL-1 alpha , rrIL-1 alpha , recombinant mouse (rm) IL-1 alpha , and rmIL-1▀ is observed.
gene symbol :
IL1B
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Human IL-1ss/IL-1F2 antibody by Western Blot.
applications :
Simple Western,ELISA Capture (Matched Antibody Pair),Immunocytochemistry,Affinity Chromatography,Antibody Array Development,Array Development,Bioassay,Electrochemiluminescent Assay,ELISA (Capture),ELISA Development,ELISA Development (Capture),Luminex Development,Neutralizing,Immunohistochemistry,Western Blot,Neutralization
USD :
469 USD
alt names :
catabolin, IL-1, IL1 beta, IL-1 beta, IL-1b, IL1B, IL1-BETA, IL-1F2, IL1F2IL-1 beta, interleukin 1, beta, interleukin-1 beta, preinterleukin 1 beta, pro-interleukin-1-beta
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.