product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse CXCL4/PF4 Antibody
catalog :
MAB595-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
459 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
140910
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
R&D Systems product webpage
citations: 6
Reference
Zhang X, Takeuchi T, Takeda A, Mochizuki H, Nagai Y. Comparison of serum and plasma as a source of blood extracellular vesicles: Increased levels of platelet-derived particles in serum extracellular vesicle fractions alter content profiles from plasma extracellular vesicle fractions. PLoS ONE. 2022;17:e0270634 pubmed publisher
Wichaiyo S, Lax S, Montague S, Li Z, Grygielska B, Pike J, et al. Platelet glycoprotein VI and C-type lectin-like receptor 2 deficiency accelerates wound healing by impairing vascular integrity in mice. Haematologica. 2019;: pubmed publisher
Barwari T, Eminaga S, Mayr U, Lu R, Armstrong P, Chan M, et al. Inhibition of profibrotic microRNA-21 affects platelets and their releasate. JCI Insight. 2018;3: pubmed publisher
Lindsey M, Jung M, Yabluchanskiy A, Cannon P, Iyer R, Flynn E, et al. Exogenous CXCL4 infusion inhibits macrophage phagocytosis by limiting CD36 signalling to enhance post-myocardial infarction cardiac dilation and mortality. Cardiovasc Res. 2019;115:395-408 pubmed publisher
Tkaczynski E, Arulselvan A, Tkaczynski J, Avery S, Xiao L, Torok Storb B, et al. 2-O, 3-O desulfated heparin mitigates murine chemotherapy- and radiation-induced thrombocytopenia. Blood Adv. 2018;2:754-761 pubmed publisher
Ren Q, Wimmer C, Chicka M, Ye S, Ren Y, Hughson F, et al. Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis. Blood. 2010;116:869-77 pubmed publisher
product information
brand :
R&D Systems
master code :
MAB595
SKU :
MAB595-100
product name :
Mouse CXCL4/PF4 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
seo description :
The Mouse CXCL4/PF4 Antibody from R&D Systems is a rat monoclonal antibody to CXCL4/PF4. This antibody reacts with mouse. The Mouse CXCL4/PF4 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,ELISA Capture (Matched Antibody Pair).
target :
CXCL4/PF4
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
140910
conjugate :
Unconjugated
dilution :
Western Blot 2 ug/mL, ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
host :
Rat
immunogen :
E. coli -derived recombinant mouse CXCL4/PF4, Val30-Ser105, Accession # Q9Z126
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse CXCL4/PF4 in ELISAs and Western blots. In ELISAs, this antibody does not cross-react or interfere recombinant human (rh) CXCL/PF4, recombinant mouse (rm) CXCL9/MIG, rmGM-CSF, rmCXCL11/I-TAC, rhCXCL8/IL-8, rmIL-5, or rhCXCL10/IP-10. In Western blots, no cross-reactivity was observed with rhGCP-2, rmGCP-2, rhGRO alpha , rhGRO▀, rhGRO gamma , rhMIP-1 alpha , rmMIP-1 alpha , rmMIP-1▀, rhMIP-1 delta , rmMIP-1 gamma , rmMIP-2, rhMIP-3 alpha , rmMIP-3 alpha , rrMIP-3 alpha , rhMIP-3▀, or rmMIP-3▀,
gene symbol :
PF4
top caption :
Detection of Mouse CXCL4/PF4 antibody by Western Blot.
accessionNumbers :
Q9Z126
applications :
ELISA Capture (Matched Antibody Pair),Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin
USD :
459 USD
alt names :
chemokine (C-X-C motif) ligand 4, C-X-C motif chemokine 4, CXCL4iroplact, Iroplact, MGC138298, Oncostatin-A, PF4, PF-4, platelet factor 4, SCYB4oncostatin-A
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.