product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse CCR6 Antibody
catalog :
MAB590-100
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
140706
reactivity :
human, mouse
application :
immunohistochemistry, neutralization, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 4e
Shi Z, Takeuchi T, Nakanishi Y, Kato T, Beck K, Nagata R, et al. A Japanese Herbal Formula, Daikenchuto, Alleviates Experimental Colitis by Reshaping Microbial Profiles and Enhancing Group 3 Innate Lymphoid Cells. Front Immunol. 2022;13:903459 pubmed publisher
Akoolo L, Djokić V, Rocha S, Ulloa L, Parveen N. Sciatic-Vagal Nerve Stimulation by Electroacupuncture Alleviates Inflammatory Arthritis in Lyme Disease-Susceptible C3H Mice. Front Immunol. 2022;13:930287 pubmed publisher
Muschaweckh A, Petermann F, Korn T. IL-1? and IL-23 Promote Extrathymic Commitment of CD27+CD122- ?? T Cells to ??T17 Cells. J Immunol. 2017;199:2668-2679 pubmed publisher
Geherin S, Gómez D, Glabman R, Ruthel G, Hamann A, Debes G. IL-10+ Innate-like B Cells Are Part of the Skin Immune System and Require α4β1 Integrin To Migrate between the Peritoneum and Inflamed Skin. J Immunol. 2016;196:2514-2525 pubmed publisher
Boyle S, Faulkner J, McColl S, Kochetkova M. The chemokine receptor CCR6 facilitates the onset of mammary neoplasia in the MMTV-PyMT mouse model via recruitment of tumor-promoting macrophages. Mol Cancer. 2015;14:115 pubmed publisher
Liu J, Ke F, Xu Z, Liu Z, Zhang L, Yan S, et al. CCR6 is a prognostic marker for overall survival in patients with colorectal cancer, and its overexpression enhances metastasis in vivo. PLoS ONE. 2014;9:e101137 pubmed publisher
Zhao P, Hou L, Farley K, Sundrud M, REMOLD O DONNELL E. SerpinB1 regulates homeostatic expansion of IL-17+ ?? and CD4+ Th17 cells. J Leukoc Biol. 2014;95:521-30 pubmed publisher
Caballero Campo P, Buffone M, Benencia F, Conejo Garcia J, Rinaudo P, Gerton G. A role for the chemokine receptor CCR6 in mammalian sperm motility and chemotaxis. J Cell Physiol. 2014;229:68-78 pubmed publisher
Hu S, Xiong N. Programmed downregulation of CCR6 is important for establishment of epidermal ??T cells by regulating their thymic egress and epidermal location. J Immunol. 2013;190:3267-75 pubmed publisher
Comerford I, Litchfield W, Kara E, McColl S. PI3K? drives priming and survival of autoreactive CD4(+) T cells during experimental autoimmune encephalomyelitis. PLoS ONE. 2012;7:e45095 pubmed publisher
Baptista A, Olivier B, Goverse G, Greuter M, Knippenberg M, Kusser K, et al. Colonic patch and colonic SILT development are independent and differentially regulated events. Mucosal Immunol. 2013;6:511-21 pubmed publisher
Mabuchi T, Singh T, Takekoshi T, Jia G, Wu X, Kao M, et al. CCR6 is required for epidermal trafficking of γδ-T cells in an IL-23-induced model of psoriasiform dermatitis. J Invest Dermatol. 2013;133:164-71 pubmed publisher
Liu J, Zhang N, Li Q, Zhang W, Ke F, Leng Q, et al. Tumor-associated macrophages recruit CCR6+ regulatory T cells and promote the development of colorectal cancer via enhancing CCL20 production in mice. PLoS ONE. 2011;6:e19495 pubmed publisher
Röhrl J, Yang D, Oppenheim J, Hehlgans T. Human beta-defensin 2 and 3 and their mouse orthologs induce chemotaxis through interaction with CCR2. J Immunol. 2010;184:6688-94 pubmed publisher
product information
brand :
R&D Systems
master code :
MAB590
SKU :
MAB590-100
product name :
Mouse CCR6 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse CCR6 Antibody from R&D Systems is a rat monoclonal antibody to CCR6. This antibody reacts with mouse. The Mouse CCR6 Antibody has been validated for the following applications: ELISA Development (Capture),Flow Cytometry,Neutralization,Immunohistochemistry,Immunohistochemistry-Frozen,CyTOF-ready.
target :
CCR6
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
140706
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Flow Cytometry 0.25 ug/10^6 cells, Immunohistochemistry 8-25 ug/mL, CyTOF-ready
host :
Rat
immunogen :
RBL-1 rat basophilic leukemia cell line transfected with mouse CCR6, Met1-Met367, Accession # O54689
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse CCR6-transfected rat RBL cells but not the parent cell line or cells transfected with mouse CCR5.
gene symbol :
CCR6
top caption :
Detection of CCR6 antibody in Mouse Splenocytes antibody by Flow Cytometry.
accessionNumbers :
O54689
applications :
CyTOF-ready,ELISA Development (Capture),Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Frozen,Neutralization
USD :
499 USD
alt names :
BN-1, CC-CKR-6, CCR6, CCR-6, CD196, CD196 antigen, chemokine (C-C motif) receptor 6, CKRL3, CKR-L3, CKR-L3G-protein coupled receptor 29, CKRL3LARC receptor, CMKBR6, CMKBR6STRL22, DRY6, GPR29, GPR29C-C CKR-6, GPRCY4, GPR-CY4, GPRCY4DRY-6, lymphocyte, 22, STRL22
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.