product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse Siglec-E Antibody
catalog :
MAB5806
quantity :
100 ug (also 25 ug)
price :
459 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
750620
reactivity :
human, mouse
application :
flow cytometry
more info or order :
citations: 3
Reference
Dharmadhikari G, Stolz K, Hauke M, Morgan N, Varki A, de Koning E, et al. Siglec-7 restores β-cell function and survival and reduces inflammation in pancreatic islets from patients with diabetes. Sci Rep. 2017;7:45319 pubmed publisher
Wu Y, Ren D, Chen G. Siglec-E Negatively Regulates the Activation of TLR4 by Controlling Its Endocytosis. J Immunol. 2016;197:3336-3347 pubmed
Walker D, Whetzel A, Lue L. Expression of suppressor of cytokine signaling genes in human elderly and Alzheimer's disease brains and human microglia. Neuroscience. 2015;302:121-37 pubmed publisher
product information
master code :
MAB5806
SKU :
MAB5806
product name :
Mouse Siglec-E Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse Siglec-E Antibody from R&D Systems is a rat monoclonal antibody to Siglec-E. This antibody reacts with human,mouse. The Mouse Siglec-E Antibody has been validated for the following applications: Flow Cytometry,CyTOF-ready.
target :
Siglec-E
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
750620
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse Siglec-E, Gln19-Phe354, Accession # Q91Y57
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects mouse Siglec-E in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse (rm) Siglec-3/CD33 or rmSiglec-F is observed.
gene symbol :
Siglece
top caption :
Detection of Mouse Siglec-E antibody in Mouse Splenocytes.
accessionNumbers :
Q91Y57
applications :
Flow Cytometry,CyTOF-ready
USD :
459 USD
alt names :
CD170;CD33L2;OBBP2;OB-BP2;Sialic acid-binding Ig-like lectin 5;SIGLEC5;SIGLEC-5, SiglecE
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.