CX3CL1/Fractalkine Chemokine Domain Antibody | R&D Systems MAB571-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

CX3CL1/Fractalkine Chemokine Domain Antibody

catalog :

MAB571-100

quantity :

100 ug (also 500 ug, 25 ug)

price :

459 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

126315

reactivity :

mouse

application :

western blot, ELISA, neutralization

more info or order :

R&D Systems product webpage

citations: 6

Reference
Rappl P, R xf6 sser S, Maul P, Bauer R, Huard A, Schreiber Y, et al. Inhibition of mPGES-1 attenuates efficient resolution of acute inflammation by enhancing CX3CL1 expression. Cell Death Dis. 2021;12:135 pubmed publisher
Mizoguchi M, Ishida Y, Nosaka M, Kimura A, Kuninaka Y, Yahata T, et al. Prevention of lipopolysaccharide-induced preterm labor by the lack of CX3CL1-CX3CR1 interaction in mice. PLoS ONE. 2018;13:e0207085 pubmed publisher
Okuma A, Hanyu A, Watanabe S, Hara E. p16Ink4a and p21Cip1/Waf1 promote tumour growth by enhancing myeloid-derived suppressor cells chemotaxis. Nat Commun. 2017;8:2050 pubmed publisher
Simons B, Ferrini M, Carvalho S, Bassett D, Jaffar Z, Roberts K. PGI2 Controls Pulmonary NK Cells That Prevent Airway Sensitization to House Dust Mite Allergen. J Immunol. 2017;198:461-471 pubmed
Mills J, Alabanza L, Mahamed D, Bynoe M. Extracellular adenosine signaling induces CX3CL1 expression in the brain to promote experimental autoimmune encephalomyelitis. J Neuroinflammation. 2012;9:193 pubmed
Tang L, Hu H, Hu P, Lan Y, Peng M, Chen M, et al. Gene therapy with CX3CL1/Fractalkine induces antitumor immunity to regress effectively mouse hepatocellular carcinoma. Gene Ther. 2007;14:1226-34 pubmed

image

image 1 :

Chemotaxis Induced by CX3CL1/Fractalkine and Neutralization by Mouse CX3CL1/Fractalkine Antibody.

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

MAB571

SKU :

MAB571-100

product name :

CX3CL1/Fractalkine Chemokine Domain Antibody

Description :

The Mouse CX3CL1/Fractalkine Chemokine Domain Antibody from R&D Systems is a rat monoclonal antibody to CX3CL1/Fractalkine. This antibody reacts with mouse. The Mouse CX3CL1/Fractalkine Chemokine Domain Antibody has been validated for the following applications: Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair).

target :

CX3CL1/Fractalkine

category :

Primary Antibodies

unit size :

100 ug (also 500 ug, 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

126315

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse CX3CL1/Fractalkine, S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse CX3CL1/Fractalkine, and E. coli -derived recombinant mouse CX3CL1/Fractalkine

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse CX3CL1/Fractalkine in Western blots. In direct ELISAs, this antibody shows 100% cross-reactivity with the chemokine domain of recombinant human (rh) CX3CL1, 13% cross-reactivity with rhCX3CL1, and 50% cross-reactivity with recombinant rat CX3CL1.

gene symbol :

CX3CL1

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

applications :

Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair)

USD :

459 USD

alt names :

ABCD-3, C3Xkine, chemokine (C-X3-C motif) ligand 1, CX3C membrane-anchored chemokine, CXC3, CXC3C, FKN, fractalkine, Neurotactin, neurotactin), NTNsmall inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, NTTSmall-inducible cytokine D1, SCYD1C-X3-C motif chemokine 1, small inducible cytokine subfamily D (Cys-X3-Cys), member-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage