Human FOLR1 Antibody | R&D Systems MAB5646 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human FOLR1 Antibody

catalog :

MAB5646

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

548908

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 12

Reference
Spicer J, Basu B, Montes A, Banerji U, Kristeleit R, Miller R, et al. Safety and anti-tumour activity of the IgE antibody MOv18 in patients with advanced solid tumours expressing folate receptor-alpha: a phase I trial. Nat Commun. 2023;14:4180 pubmed publisher
Yokoi A, Ukai M, Yasui T, Inokuma Y, Hyeon Deuk K, Matsuzaki J, et al. Identifying high-grade serous ovarian carcinoma-specific extracellular vesicles by polyketone-coated nanowires. Sci Adv. 2023;9:eade6958 pubmed publisher
Bax H, Chauhan J, Stavraka C, Santaolalla A, Osborn G, Khiabany A, et al. Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes. Br J Cancer. 2023;128:342-353 pubmed publisher
Song J, Sokoll L, Chan D, Zhang Z. Validation of Serum Biomarkers That Complement CA19-9 in Detecting Early Pancreatic Cancer Using Electrochemiluminescent-Based Multiplex Immunoassays. Biomedicines. 2021;9: pubmed publisher
Mondal T, Shivange G, Tihagam R, Lyerly E, Battista M, Talwar D, et al. Unexpected PD-L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies. EMBO Mol Med. 2021;13:e12716 pubmed publisher
Li N, Zuo H, Chen L, Liu H, Zhou J, Yao Y, et al. Circulating Tumor Cell Detection In Epithelial Ovarian Cancer Using Dual-Component Antibodies Targeting EpCAM And FRα. Cancer Manag Res. 2019;11:10939-10948 pubmed publisher
Taniuchi K, Yawata T, Tsuboi M, Ueba T, Saibara T. Efficient delivery of small interfering RNAs targeting particular mRNAs into pancreatic cancer cells inhibits invasiveness and metastasis of pancreatic tumors. Oncotarget. 2019;10:2869-2886 pubmed publisher
Chen L, Peng M, Li N, Song Q, Yao Y, Xu B, et al. Combined use of EpCAM and FRα enables the high-efficiency capture of circulating tumor cells in non-small cell lung cancer. Sci Rep. 2018;8:1188 pubmed publisher
Roti G, Qi J, Kitara S, Sanchez Martin M, Saur Conway A, Varca A, et al. Leukemia-specific delivery of mutant NOTCH1 targeted therapy. J Exp Med. 2018;215:197-216 pubmed publisher
Yang Y, He L, Liu Y, Xia S, Fang A, Xie Y, et al. Promising Nanocarriers for PEDF Gene Targeting Delivery to Cervical Cancer Cells Mediated by the Over-expressing FR?. Sci Rep. 2016;6:32427 pubmed publisher
Kelemen L, Brenton J, Parkinson C, C Whitaker H, Piskorz A, Csizmadi I, et al. Conditions associated with circulating tumor-associated folate receptor 1 protein in healthy men and women. PLoS ONE. 2014;9:e96542 pubmed publisher
Rudman S, Josephs D, Cambrook H, Karagiannis P, Gilbert A, Dodev T, et al. Harnessing engineered antibodies of the IgE class to combat malignancy: initial assessment of Fc?RI-mediated basophil activation by a tumour-specific IgE antibody to evaluate the risk of type I hypersensitivity. Clin Exp Allergy. 2011;41:1400-13 pubmed publisher

product information

master code :

MAB5646

SKU :

MAB5646

product name :

Human FOLR1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human FOLR1 Antibody from R&D Systems is a mouse monoclonal antibody to FOLR1. This antibody reacts with human. The Human FOLR1 Antibody has been validated for the following applications: Immunocytochemistry,Flow Cytometry,ELISA Development,ELISA Development (Capture),Western Blot,ELISA Capture,ELISA Detection,ELISA Capture (Matched Antibody Pair),CyTOF-ready,Knockout Validated.

target :

FOLR1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

548908

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant human FOLR1, Arg25-Met233, Accession # P15328

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human FOLR1 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human FOLR2, 3 or 4 is observed.

gene symbol :

FOLR1

Antibody validation :

Knockout/Knockdown

top caption :

Detection of Human FOLR1 antibody by Western Blot.

accessionNumbers :

P15328

applications :

Flow Cytometry,Immunocytochemistry,ELISA Development,ELISA Development (Capture),Western Blot,ELISA Capture,ELISA Detection,ELISA Capture (Matched Antibody Pair),CyTOF-ready,Knockout Validated

USD :

499 USD

alt names :

Adult folate-binding protein, FBP, folate binding protein, Folate receptor 1, folate receptor 1 (adult), folate receptor alpha, Folate receptor, adult, Folbp1, FOLR, FR-alpha, KB cells FBP, MOv18, Ovarian tumor-associated antigen MOv18

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage