Siglec-1/CD169 Antibody | R&D Systems MAB5610 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Siglec-1/CD169 Antibody

catalog :

MAB5610

quantity :

100 ug (also 25 ug)

price :

415 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

645608

reactivity :

mouse

application :

western blot, flow cytometry

more info or order :

R&D Systems product webpage

citations: 4

Reference
Wu Y, Lan C, Ren D, Chen G. Induction of Siglec-1 by Endotoxin Tolerance Suppresses the Innate Immune Response by Promoting TGF-?1 Production. J Biol Chem. 2016;291:12370-82 pubmed publisher
Zheng Q, Hou J, Zhou Y, Yang Y, Cao X. Type I IFN-Inducible Downregulation of MicroRNA-27a Feedback Inhibits Antiviral Innate Response by Upregulating Siglec1/TRIM27. J Immunol. 2016;196:1317-26 pubmed publisher
Honke N, Shaabani N, Merches K, Gassa A, Kraft A, Ehrhardt K, et al. Immunoactivation induced by chronic viral infection inhibits viral replication and drives immunosuppression through sustained IFN-I responses. Eur J Immunol. 2016;46:372-80 pubmed publisher
Gerlini A, Colomba L, Furi L, Braccini T, Manso A, Pammolli A, et al. The role of host and microbial factors in the pathogenesis of pneumococcal bacteraemia arising from a single bacterial cell bottleneck. PLoS Pathog. 2014;10:e1004026 pubmed publisher

image

image 1 :

Detection of Siglec-1/CD169 antibody in RAW 264.7 Mouse Cell Line antibody by Flow Cytometry.

product information

brand :

R&D Systems

master code :

MAB5610

SKU :

MAB5610

product name :

Siglec-1/CD169 Antibody

description :

The Mouse Siglec-1/CD169 Antibody from R&D Systems is a rat monoclonal antibody to Siglec-1/CD169. This antibody reacts with mouse. The Mouse Siglec-1/CD169 Antibody has been validated for the following applications: Western Blot, Flow Cytometry, CyTOF-ready.

target :

Siglec-1/CD169

category :

Primary Antibodies

unit sizes :

100 ug (also 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

645608

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse Siglec-1/CD169, Thr20-Leu1639 (predicted), Accession # Q62230

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse Siglec-1/CD169 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human Siglec-1, -5, -6, -7, -8, -9, -10, -11, -14, recombinant mouse Siglec-2, -3, -E, -F, -G, or -H is observed.

gene symbol :

SIGLEC1

accessionNumbers :

Q62230

applications :

Western Blot, Flow Cytometry, CyTOF-ready

USD :

415 USD

alt names :

CD169, FLJ00051, sialic acid binding Ig-like lectin 1, sialoadhesin, sialoadhesin, Siglec1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage